Cardiovascular complications associated with cocaine use.
Home Monitoring technology: transmission steps in this fully automatic system.
Potential biological pathways influenced by statins which could reduce risk of thromboembolic disease.
Reduced mortality in former Tour de France participants: the benefits from intensive exercise or a select genetic tour de force? - Figure 1
Schematic representation demonstrating the potential effects of endurance cycling on longevity.
Proposed model illustrating the multifactorial aetiology of cardiac and skeletal muscle atrophy in patients with cancer cachexia. The interplaying pathways leading to cardiac and skeletal muscle atrophy outlined in this figure are non-exhaustive and remain incompletely delineated. IGF-1, insulin-like growth factor-1; IL, interleukin; LVEF, left ventricular ejection fraction; TNF-α, tumour necrosis factor-α.
‘tis bitter cold and I am sick at heart’: establishing the relationship between outdoor temperature, blood pressure, and cardiovascular mortality
Environmental temperature, seasonality, and cardiovascular (CV) health: possible interactions. Seasonality is associated with significant changes in blood pressure and CV mortality. However the underlying mechanisms leading to this outcome are unclear, including outdoor temperature, but also sunlight exposure, weather conditions and air pollution, socioeconomic status, changes in dietary and exercise habits, circadian rhytms and sleep alterations and conceivably several unknown factors.
The decision on the type of treatment of a chronic total occlusion (CTO) is dependent on many factors: the severity of symptoms with optimal medical therapy (OMT), the extent of ischaemia (exercise ECG or non-invasive imaging), and the presence of myocardial viability (myocardial function by echo or late gadolinium enhancement by cardiac magnetic resonance) are the main determinants of revascularization. The decision on how to revascularize depends on CTO complexity, local percutnaeous coronary intervention (PCI) expertise for complex CTO procedures, and the presence of multivessel disease and co-morbidities that affect PCI and coronary artery bypass (CABG) risks. Evidence that successful revascularization improves cardiac mortality is still preliminary, but may emerge as a potent indication supporting revascularization strategies in patients with CTO. MACE, major adverse cardiovascular and cerebrovascular event.