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European Heart Journal 1980 1(4):309-313;
Copyright © 1980 by the European Society of Cardiology.
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© 1980 The European Society of Cardiology

Propafenone — a new antiarrhythmic drug

L. SEIPEL and G. BREITHARDT

Med. Klinik B Universität Düsseldorf Moorenstr. 5, D-4 Düsseldorf, West Germany

Received 7 May 1980; .

Requests for reprints to: Prof. Dr. med. L. Seipel, Med. Klinik B, Universität Düsseldorf, Moorenstr. 5, D–4 Düsseldorf, West Germany.

Propafenone is a new antiarrhythmic drug with class-I action and some additional sympathicolytic activities. Due to its pharmacokinetic properties the drug is appropriate for long-term oral treatment. Propafenone is especially successful in suppressing ventricular arrhythmias and in preventing tachycardias in patients with WPW syndrome. So far, final conclusions concerning the side effects cannot be drawn.

Key Words: New antiarrhythmic drug • clinical pharmacology • clinical electrophysiology


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