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European Heart Journal 1989 10(12):1115-1117;
Copyright © 1989 by the European Society of Cardiology.
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© 1989 The European Society of Cardiology

Successful thrombolysis on a mechanical tricuspid prosthesis

M. A. PRIETO PALOMINO, M. J. RUIZ DE ELVIRA, F. SANCHEZ LLORENTE, E. TORRADO, J. L. CASTILLO, N. GONZALEZ DE VEGA and A. GARIJO GALVE

Servicio de Medicina Intensiva, Hospital Materno Infantil Malaga, Spain

Received 3 October 1988; revised 4 January 1989; .

Correspondence address: Miguel Angel Prieto Palomino, Servicio de Medicina Intensiva, Hospital Materno Infantil, Calle Arroyo de los Angeles s/n, 29011 Malaga, Espana

Abstract

Recombinant tissue-type plasminogen activator (rt-PA) is presently used for the treatment of different clinical entities, mostly myocardial infarction. Its use for treatment of thrombotic dysfunction of prosthetic cardiac valves is more recent and has been only rarely reported. A 33-year-old woman with a St Jude Medical prosthesis in the tricuspid position, had suffered from thrombotic dysfunction of her prosthesis for more than 2 months. She was treated with rt-PA, and after infusion of 70 mg, the prosthesis functioned normally. She showed a moderate systemic fibrinolytic state associated with mild bleeding complications.

Key Words: Recombinant tissue-type plasminogen activator • prosthetic tricuspid valve thrombosis • thrombolysis • St Jude Medical prosthesis • thrombotic dysfunction


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