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European Heart Journal 1989 10(6):577-580;
Copyright © 1989 by the European Society of Cardiology.
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© 1989 The European Society of Cardiology

Inflammatory arteritis with reversible coronary localization in a 70-year-old woman

P. CHERIN*,, H. AWADA*, S. CATTAN{dagger} and B. AMOR*

*Clinique de Rhumatolgie Paris, France
{dagger}Service de Cardiologie, Hâpital Cochin Paris, France

Received 19 September 1988; accepted 20 December 1988.

Reprint requests to: Patrick Cherin M.D., Service de Medecine Interne du Pt. Dormont, Hdpiul Antoine Bedere, 157 rue de la porte de Tnvaux, 92141 Ctamart, France.

Abstract

Giant cell arteritis with coronary involvement is an uncommon event, often discovered at autopsy after a myocardial infarction. We report the case of a 70–year–old female with unstable angina pectoris persisting despite angioplasty and antianginal treatment, associated with chronically increased erythrocyte sedimentation rate. Temporal artery biopsy was negative but ophthalmic assessment showed sequelae of ischaemic optical neuritis. Response to prednisone therapy was striking, with complete disappearance of angina pectoris, normalization of erythrocyte sedimentation rate and decreased thallium uptake at scintigraphy. This is the first case of giant cell arteritis of the coronary arteries seen after attempted therapy with percutaneous transluminal coronary angioplasty.

Such findings justify considering giant cell arteritis each time a case of coronary manifestations with increased erythrocyte sedimentation rate resists medical treatment, or recurs after coronary angioplasty.

Key Words: Inflammatory arteritis • giant cell arteritis • angina pectoris • percutaneous transluminal coronary angioplasty


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