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European Heart Journal 1989 10(Supplement G):42-48; doi:10.1093/eurheartj/10.suppl_G.42
Copyright © 1989 by the European Society of Cardiology.
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© 1989 The European Society of Cardiology

Five years of angiographic and clinical follow-up after successful percutaneous transluminal coronary angioplasty

P. Guiteras, L. Tomas, C. Varas, J. M. Augé, M. Masotti, C. Crexells and A. Oriol

Department of Hemodynamics, Hospital de la Santa Creu and Sant Pau Barcelona, Spain

Address for correspondence: P. Guiteras, Hemodinàmica, Hospital de la Sta. Creu i Sant Pau. Avda, Pare Claret 167. Barcelona 08025, Spain

The first 67 consecutive patients (77 lesions) who underwent successful coronary angioplasty (PTCA) at our hospital were clinically followed with serial exercise testing over a 5-year (4 to 7) observation period. Two sequential angiographic controls were performed 6·9 ± 4 (64 patients) and 49 ± 21.6 (42 patients) months after PTCA. The 5-year risk of cardiac death was 8%, of myocardial infarction 2%, of coronary artery bypass grafting 16% and of repeat PTCA 8%. At 5 years, 67% of the patients remain asymptomatic. Restenosis ≥ 70% diameter was observed within the first year after PTCA in 30% of the patients. Progression of coronary artery disease (CAD) was observed in 13 patients (20%). In the first angiographic.control, CAD progression was 4% (3/77) in dilated and 3% (3/115) in non-dilated arteries (ns). In the second angiographic control, it was 7% (3/45) and 10% (8/81), respectively (ns).

Thus good clinical and angiographic results are still observed after 5 years. Restenosis is an early, self-limited, time-restricted phenomenon that occurs in 30% of patients. Angioplasty does not appear to accelerate CAD progression.

Key Words: Angioplasty • cardiac event-free • restenosis • progression of coronary artery disease


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