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European Heart Journal 1990 11(11):1029-1032;
Copyright © 1990 by the European Society of Cardiology.
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© 1990 The European Society of Cardiology

Plasma viscosity, fibrinogen and haematocrit in the course of unstable angina

J. FUCHS, A. PINHAS, E. DAVIDSON, Z. ROTENBERG, J. AGMON and I. WEINBERGER

Department of Medicine 'A' and the Israel and lone Massada Center for Heart Diseases, Beilinson Medical Center, Petah Tikva and the Tel Aviv University Sackler School of Medicine Tel Aviv, Israel

Received 1 January 1989; revised 9 November 1989; .

Address for reprints: J. Fuchs, M. D., Department of Medicine ‘A’, Beilinson Medical Center, PetahTikva 49100, Israel.

Abstract

Plasma viscosity, fibrinogen and haematocrit were measured in 80 patients with unstable angina on the 1st, 2nd and 5th day of hospitalization. In the group of patients who developed acute myocardial infarction (AMI) during hospitalization (20 patients), plasma viscosity was elevated during the entire observation period (1.69 ±0.05 cp, normal range 1.38–1.48 cp), while in patients who did not develop AMI, plasma viscosity was only mildly elevated (1.59±0.05 cp, P<0.001 vs the group who developed AMI) and tended to normalize towards the 5th day of hospitalization. Fibrinogen and haematocrit showed similar variations between the two groups. In a group of 20 patients who received heparin, the studied parameters were similar to the group who did not develop AMI. The importance of haemorheological factors in the clinical course of unstable angina is thus emphasized.

Key Words: Plasma viscosity • fibrinogen • haematocrit • unstable angina


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