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European Heart Journal 1990 11(11):990-996;
Copyright © 1990 by the European Society of Cardiology.
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© 1990 The European Society of Cardiology

Distensibility of the ascending aorta: comparison of invasive and non-invasive techniques in healthy men and in men with coronary artery disease

C. STEFANADIS, C. STRATOS, H. BOUDOULAS, C. KOUROUKLIS and P. TOUTOUZAS

Department of Cardiology, Athens Medical School Athens, Greece

Received 25 September 1989; revised 12 December 1990; .

Correspondence; Christodoulos Stefanadis MD. Tepeleniou 9 str., Paleo Psychico, Athens, 154 52, Greece

Abstract

Distensibility of the ascending aorta, measured non-invasively, was compared with values obtained by invasive techniques in 46 males (30 patients with coronary artery disease and 16 age-matched normal subjects). Aortic diameters were measured at a level 3 cm above the aortic valve using both echocardiographic and angiographic techniques. Aortic distensibility was calculated from the aortic diameters and aortic pressure or brachial artery pressure using the formula: 2 x (change in aortic diameter) /(diastolic aortic diameter) x (change in aortic pressure). Distensibility of the ascending aorta determined non-invasively was closely related to that obtained by direct measurements (r = 0.949, P<0.001). Patients with coronary artery disease had similar pressures, but markedly lower distensibility than normal subjects, as shown by both invasive and non-invasive techniques. The results indicate that aortic distensibility in patients with coronary artery disease can be obtained non-invasively with a high degree of accuracy.

Key Words: Aortic distensibility • echocardiography • coronary artery disease


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