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European Heart Journal 1990 11(Supplement E):100-104; doi:10.1093/eurheartj/11.suppl_E.100
Copyright © 1990 by the European Society of Cardiology.
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© 1990 The European Society of Cardiology

Malondialdehyde, modified lipoproteins, and atherosclerosis

M. E. Haberland*,, D. Fong* and L. Cheng{dagger}

* Division of Cardiology, UCLA School of Medicine Los Angeles, California, U.S.A.
{dagger} Department of Pathology, UCLA School of Medicine Los Angeles, California, U.S.A.

Address for correspondence: Dr Margaret E. Haberland, Division of Cardiology CHS 47-123, Department of Medicine, UCLA Center for the Health Sciences, Los Angeles, California 90024-1679, U.S.A.

It is likely that identification of the mechanisms releasing malondialdehyde and other peroxidative decomposition products in the arterial wall will provide new insights into the sequence of biochemical and cellular events in the pathogenesis of atherosclerosis and ultimately may lead to development of strategies for the intervention and reduction of the incidence of atherosclerotic events.

Key Words: Malondialdehyde • low density lipoprotein • oxidized lipoproteins • arterial foam cell formation


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