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European Heart Journal 1990 11(Supplement I):114-123; doi:10.1093/eurheartj/11.suppl_I.114
Copyright © 1990 by the European Society of Cardiology.
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© 1990 The European Society of Cardiology

Systolic time intervals as indicators for cardiac function in rat models for heart failure

R. G. Schoemaker and J. F. M. Smits

Department of Pharmacology, University of Limburg Maastricht, The Netherlands

Correspondence: Jos F. M. Smits, Department of Pharmacology, University of Limburg, P0 Box 616, Maastricht, The Netherland

Measurement of the pre-ejection period (PEP) can give valuable information on myocardialfunction in rats. Depressed cardiac function is accompanied by prolongation of PEP, which shortens when cardiac function improves. Left ventricular ejection time (LVET) may be shortened with ageing in spontaneously hypertensive rats.

Key Words: Myocardial infarction • hypertension • stroke volume • peripheral resistance • pre-ejection period • left ventricular ejection time • inotropes • vasodilators


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