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European Heart Journal 1991 12(10):1081-1083;
Copyright © 1991 by the European Society of Cardiology.
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© 1991 The European Society of Cardiology

Reduced occurrence of atrial fibrillation in acute myocardial infarction treated with streptokinase

F. E. NIELSEN, H. T. SøRENSEN, J. H. CHRISTENSEN, L. RAVN and S. E. RASMUSSEN

Department of Cardiology, Aalborg Hospital South Aalborg, Denmark

Received 19 April 1990; revised 29 October 1990; .

Correspondence: Finn Erland Nielsen, MD, Department of Cardiology Gentofte University Hospital, DK Hellerup, Denmark

Abstract

In a hisiorical follow-up study of 152 hospital patients with acute myocardial infarction, the frequency of life-threatening arrhythmias (ventricular fibrillation, sustained ventricular tachycardia, 3rd degree AV-block, 2nd degree AV-block (Mobitz type II), and asystole) and atrialfibrillation in 76 patients treated with streptokinase was compared with their frequency in 76 patients who did not receive a thrombolytic therapy.

Among those treated with streptokinase two patients (3%) developed atrial fibrillation, compared with 12 (16%) in the control group (P=0·009 Life-threatening arrhythmias occurred with equal frequency in the two groups. Further studies should confirm and clar the mechanism of the reduced frequency of a trial fibrillation in the streptokinase-treated patients.

Key Words: Acute myocardial infarction • streptokinase • atrial fibrillation


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