Copyright © 1991 by the European Society of Cardiology.
© 1991 The European Society of Cardiology
Ventricular fibrillation in the Wolff-Parkinson-White syndrome
*Department of Cardiology, University Hospital Maastricht The Netherlands
**Hospital San Pablo Barcelona, Spain
***Medizinische Klinik Universität Düsseldorf Federal Republic of Germany
||Medizinische Hochschule Hannover Federal Republic of Germany
Krankenhaus Universität Eppendorf Hamburg, Federal Republic of Germany
Hôpital Lariboisiere Paris France
Hôpital Jean Rostand Ivry, France
Received 14 December 1988; revised 1 April 1990; .
Correspondence and reprint requests: Pedro Brugada, MD, FESC, Professor of Cardiology, Cardiovascular Center, OLV Hospital Moorselbaan 164, 9300 Aalst, Belgium.
Abstract
Ventricular fibrillation (VF) is a well-known but rare complication of the Wolff-Parkinson-White syndrome (WPW). Clinical and electrophysiological data of 23 patients with spontaneous VF were compared with data from 100 consecutive patients with WPW without VF but with symptomatic supraventricular tachycardia. The 23 patients were collected in a multicentre retrospective study in seven European centres. VF occurred in only one patient who was receiving anti-arrhythmic drugs, and was the first manifestation of the syndrome in six. No significant differences were found between those with VF and without VF in age, complaints of palpitations, syncope, and presence of structural heart disease. The retrograde effective refractory period of the accessory pathway, the atrial refractory period and the fastest atrial pacing rate with 1: 1 anterograde conduction over the accessory pathway were similar in both groups. Significant differences were found for sex, permanent pre-excitation on the electrocardiogram, type of documented supraventricular t achy arrhythmias, shortest RR interval 
220 ms during spontaneous atrial fibrillation (AF), inducibility of supraventricular tachycardias, ventricular effective refractory period 190 ms, mean shortest RR interval during induced AF , 180 ms and presence of multiple accessory pathways. Data from this retrospective study indicate that: (1) the anterograde conduction properties of the accessory pathway are a major determinant of the occurrence of VF in the WPW syndrome; (2) other markers for risk of VF are type of previously documented supraventricular tachyarrhythmia, documentation of more than one type of supraventricular tachycardia in the same patient and presence of two or more accessory pathways; (3) the finding of intermittent pre-excitation and a shortest RR interval during spontaneous AF longer than 220 ms, identifies a group of patients at low risk of VF.
Key Words: Sudden cardiac death • Wolff-Parkin son -White syndrome • ventricular fibrillation • atrial fibrillation • accessory pathway
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  C. Blomstrom-Lundqvist Drug treatment of supraventricular tachycardia Heart, November 1, 2009; 95(21): 1803 - 1807. [Full Text] [PDF]
|
|
|
|
 |
|
 V. Santinelli, A. Radinovic, F. Manguso, G. Vicedomini, G. Ciconte, S. Gulletta, G. Paglino, S. Sacchi, S. Sala, C. Ciaccio, et al. Asymptomatic Ventricular Preexcitation: A Long-Term Prospective Follow-Up Study of 293 Adult Patients Circ Arrhythm Electrophysiol, April 1, 2009; 2(2): 102 - 107. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 V. Santinelli, A. Radinovic, F. Manguso, G. Vicedomini, S. Gulletta, G. Paglino, P. Mazzone, G. Ciconte, S. Sacchi, S. Sala, et al. The natural history of asymptomatic ventricular pre-excitation a long-term prospective follow-up study of 184 asymptomatic children. J. Am. Coll. Cardiol., January 20, 2009; 53(3): 275 - 280. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J.#x.;n. Farré, H. J.J. Wellens, J.#x. M. Rubio, and J. Benezet CHAPTER 28 Supraventricular Tachycardias ESC Textbook of Cardiovascular Medicine, January 1, 2009; 2(1): med-9780199566990-chapter - med-9780199566990-chapter. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B. Brembilla-Perrot, F. Chometon, L. Groben, C. Tatar, J.-D. Luporsi, J. Bertrand, O. Huttin, D. Beurrier, S. Ammar, J. Cedano, et al. Are the results of electrophysiological study different in patients with a pre-excitation syndrome, with and without syncope? Europace, February 1, 2008; 10(2): 175 - 180. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. E. Marine Catheter Ablation Therapy for Supraventricular Arrhythmias JAMA, December 19, 2007; 298(23): 2768 - 2778. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. E. Jaalouk, M. G. Ozawa, J. Sun, J. Lahdenranta, R. O. Schlingemann, R. Pasqualini, and W. Arap The Original Pathologische Anatomie Leiden-Endothelium Monoclonal Antibody Recognizes a Vascular Endothelial Growth Factor Binding Site within Neuropilin-1 Cancer Res., October 15, 2007; 67(20): 9623 - 9629. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Brembilla-Perrot, F. Chometon, L. Groben, S. Ammar, J. Bertrand, C. Marcha, J.L. Cloez, A. Tisserand, O. Huttin, C. Tatar, et al. Interest of non-invasive and semi-invasive testings in asymptomatic children with pre-excitation syndrome Europace, September 1, 2007; 9(9): 837 - 843. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. J. Wellens, C. Pappone, V. Santinelli, H. J. Wellens, C. Pappone, and V. Santinelli When to Perform Catheter Ablation in Asymptomatic Patients With a Wolff-Parkinson-White Electrocardiogram Circulation, October 4, 2005; 112(14): 2201 - 2216. [Full Text] [PDF]
|
|
|
|
 |
|
 C. Pappone, V. Santinelli, F. Manguso, G. Augello, O. Santinelli, G. Vicedomini, S. Gulletta, P. Mazzone, V. Tortoriello, A. Pappone, et al. A Randomized Study of Prophylactic Catheter Ablation in Asymptomatic Patients with the Wolff-Parkinson-White Syndrome N. Engl. J. Med., November 6, 2003; 349(19): 1803 - 1811. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D Adlam and T Azeem Ventricular fibrillation during electrical cardioversion of pre-excited atrial fibrillation Postgrad. Med. J., May 1, 2003; 79(931): 297 - 299. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. M. Todd, G. J. Klein, A. D. Krahn, A. C. Skanes, and R. Yee Asymptomatic Wolff-Parkinson-White syndrome: is it time to revisit guidelines? J. Am. Coll. Cardiol., January 15, 2003; 41(2): 245 - 248. [Full Text] [PDF]
|
|
|
|
|
|
H. Oddsson, N. Edvardsson, and H. Walfridsson Episodes of atrial fibrillation and atrial vulnerability after successful radiofrequency catheter ablation in patients with Wolff-Parkinson-White syndrome Europace, January 1, 2002; 4(2): 201 - 206. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S.G. Priori, E. Aliot, C. Blomstrom-Lundqvist, L. Bossaert, G. Breithardt, P. Brugada, A.J. Camm, R. Cappato, S.M. Cobbe, C. Di Mario, et al. Task Force on Sudden Cardiac Death of the European Society of Cardiology Eur. Heart J., August 2, 2001; 22(16): 1374 - 1450. [PDF]
|
|
|
|
|
|
A young man with tachycardia Postgrad. Med. J., February 1, 2001; 77(904): 128f - 128. [Full Text]
|
|
|
|
|
|
S. S. Chugh, K. L. Kelly, and J. L. Titus Sudden Cardiac Death With Apparently Normal Heart Circulation, August 8, 2000; 102(6): 649 - 654. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. J. Heaven, J. A. Till, and S. Y. Ho Sudden death in a child with an unusual accessory connection Europace, January 1, 2000; 2(3): 224 - 227. [Abstract] [PDF]
|
|
|
|
|
|
M. A. Mathier, G. A. Rose, M. A. Fifer, M. I. Miyamoto, R. E. Dinsmore, H. H. Castano, G. W. Dec, I. F. Palacios, and M. J. Semigran Coronary endothelial dysfunction in patients with acute-onset idiopathic dilated cardiomyopathy J. Am. Coll. Cardiol., July 1, 1998; 32(1): 216 - 224. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. I. Ganz and P. L. Friedman Supraventricular Tachycardia N. Engl. J. Med., January 19, 1995; 332(3): 162 - 173. [Full Text] [PDF]
|
|