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European Heart Journal 1991 12(3):309-314;
Copyright © 1991 by the European Society of Cardiology.
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© 1991 The European Society of Cardiology

Are regional variations in ischaemic heart disease related to differences in coronary risk factors?

The project ‘myocardial infarction in mid-Sweden’

C. NERBRAND, L. OLSSON, K. SVÄRDSUDD, S. KULLMAN and G. TIBBLIN

Uppsala University, Department of Family Medicine, Uppsala and Centre for Public Health Research Karlstad, Sweden

Received 12 March 1990; revised 22 May 1990; .

Correspondence: Christina Nerbrand, MD, Centre for Public Health Research, Landstinget i VÄ rmland, S-651 82 KARLSTED, Sweden.

Abstract

In a pervious report, a large regional was reported in total mortality and mortality rate from ischaemic heart diease (IHD) in mid-Swenden. In this report, IHD prevalence and risk factor data are presented. A ostal questionnaire was sent out arandom sample of men aged 45-64 years in each of 40 communities. 14 675 men(88%) responded. Based ona validity study, IHD cases were defined as those with a history of myocardial infarction and/or angina pectoris. Age,smoking habits, anithpertensive treatment, body mass index, food habits,stress and physical activity during lesiue time were used as risk factor.

IHD prevalence showed the same geographical variation as IHD mortality, with a low prevalence in the east a high prevalence in the west. There was a moderate vartion in risk factor levels over the 40 communities. When this variation was taken into account the geographical IHD variation was somewhat smaller but still substantial. Other factors may involve socio-economics, drinking water qualities,mineral soil content or other environmental factors.Which of these cause the largestIHD variation is at present unknown, but is subject to systematic examination in theis project

Key Words: Ischaemic heart disease, • risk factors • mortality • epidemiology • smoking • cholesterol


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