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European Heart Journal 1991 12(7):1153-1162;
Copyright © 1991 by the European Society of Cardiology.
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© 1991 The European Society of Cardiology

Evaluation of the Reynolds Pathfinder II system for 24 h heart rate variability analysis

H. MØLGAARD

University Department of Cardiology Skejby Sygehus, DK, 8200 Århus N, Denmark

Received 22 March 1990; revised 1 July 1990; .

Correspondence: Henning Mølgaard MD, University Department of Cardi ology, Skejby Sygehus, DK 8200 Århus N, Denmark

Abstract

Heart rate variability (HRV) in 24-h Holter recordings is normally determined using commercially available Holter equipment. However, short-term speed variations in tape-based Holter systems have not been thoroughly investigated and recommendations for speed control are vague. In this study, overall accuracy and precision of RR interval measurement was assessed for two types of tape recorder replayed on the same Reynolds Pathfinder II system. Artificial QRS complexes spaced at exact intervals were recorded simultaneously by the two recorders. In addition, records of 118 healthy subjects were evaluated for false-positive normal-normal intervals. During replay, digital output from the pathfinder was processed by a locally developed personal computer-based HR V system.

Using the recorded crystal generated timing track (TT)for speed control and the TT dependent speed surveyor (SS), set to allow speed errors up to±3·1% mean RR per 5min. hh–1. 24 hh–1,for test tapes, corresponded exactly to true RR,for both recorders. Beat-to-beat variation, for 1000 ms test intervals, calculated as standard deviation (SD) and root mean square of successive differences (RMSSD) was 3 ms, 3 ms versus 5 ins, and 8 ms for Oxford and Tracker tapes respectively. No difference between sequential intervals exceeded±10 ms versus ±20 ms for Oxford and Tracker respectively. Reproducibility of mean RR and HRV parameters for patient records, expressed as a coefficient of variation, was 0·1–1·7%. False positive normal-normal intervals>2·3 s, due to artifacts, were found in 99 of 118 records, and these increased mean SD and RMSSD values significantly, whereas percent successive RR interval differences>50 ms were unaffected.

A crystal generated TT (60/16 Hz) and an SS allowing a maximum error of±31%, together correct speed during recording and replay to a degree that is acceptable for HRV analysis. A simple estimate of HRV counts of successive RR interval differences>50 ms is a reliable param eter as it is relatively insensitive to artifact.

Key Words: Heart rate variability • 24-h Holter monitoring • tape speed control • Reynolds Pathfinder II system


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