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European Heart Journal 1991 12(7):1205-1207;
Copyright © 1991 by the European Society of Cardiology.
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© 1991 The European Society of Cardiology

Experience of percutaneous transluminal coronary angioplasty in orthotopic cardiac transplant recipients

P. A. MULLINS, L. M. SHAPIRO, D. A. ARAVOT, J. P. SCOTT, S. R. LARGE, J. WALLWORK and P. M. SCHOFIELD

Cardiac Unit and Cardiac Transplant Research Unit, Papworth Hospital Papworth Everard, Cambridge CB3 8RE. U.K.

Received 13 June 1990; revised 9 October 1990; .

Correspondence: Dr P. A. Mullins, Senior Fellow, Transplant Unit. Papworth Hospital, Papworth Everard. Cambridge CB3 8RE. U.K.

Abstract

We evaluated the role of percutaneous transluminal coronary angioplasty (PTCA) in a series of orthotopic cardiac transplant recipients with severe epicardial coronary occlusive disease. Ten ortho topic cardiac transplant patients treated by PTCA up to March 1990 were reviewed. All had significant epicardial coronary artery lesions (>70% stenosis compared with the adjacent healthy artery) and exercise electrocardiogram or isotope perfusion evidence of myocardial ischaemia in the relevant region. Primary angiographic PTCA success was achieved in 12 of the 16 lesions attempted (75%). Mean stenosis improvement was from 80% of adjacent healthy artery (range 70–90%) to 12% (range 0–20%). Median angiographic follow-up of 9 months (2–25 months) is available for all patients. The mean recurrence rate is 33% (4 of 12 successfully treated lesions) defined as >50% reduction in the original gain at the PTCA. We have shown that PTCA is technically possible in a series of cardiac transplant recipients. The primary success and recurrence rates are comparable to the use of PTCA in conventional atherosclerotic coronary disease.

Key Words: Percutaneous transluminal coronary angioplasty • cardiac transplant


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