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European Heart Journal 1991 12(Supplement B):15-18; doi:10.1093/eurheartj/12.suppl_B.15
Copyright © 1991 by the European Society of Cardiology.
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© 1991 The European Society of Cardiology

Quantification of mitral insufficiency by radionuclide techniques

P. Rigo

Centre Hospitalier Universitaire de Liège, Nuclear Medicine Division, B-4000 Liege Belgium

Correspondence: Pierre Rigo, Nuclear Medicine Division, Centre Hospitalier Universitaire de Lège, B.35 B-4000 Sart Tilman (Liege 1), Belgium.

Radionuclide imaging is useful in the assessment of left and right ventricular function in patients with a variety of cardiac dbeases. Measurements of particular interest in patients with mitral insufficiency concern the left ventricle: ejection fraction, end-systolic volume, end-systolic volume/end-systolic pressure ratio, and the right ventricle (mainly its ejection fraction). The ejection and filling parameters of the left ventricle as well as parameters of the left atrial volume curve can also be of interest.

Quantification of mitral insuficiency relies on comparisons of total stroke volume of the left ventricle, determined relatively, or quantitatively, with the forward stroke volume. The latter is measured either as the right ventricular stroke volume (in the absence of pulmonary and tricuspid regurgitation) or as cardiac output divided by heart rate and is obtained using a radronuclide or an independent method.

Severe mitral regurgitation, as denwnstrated by a large regurgitont fraction, can occur in the presence or absence of increased end-diastolic volume. The regurgitant fraction is not heart-rate dependent and does not clearly decrease during exercise, although some variations appear to exist. Evaluation of right ventricular function during exercise can also contribute to the assessment of patients with mitral insuficiency.

Quantitative radionuclide methodr are useful to assess the severity of mitral regurgitation and its repercussions.

Key Words: Mitral insufficiency • radionuclide techniques


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