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European Heart Journal 1992 13(1):78-83;
Copyright © 1992 by the European Society of Cardiology.
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© 1992 The European Society of Cardiology

Quantitative assessment of aortic regurgitation by magnetic resonance imaging

S. GLOBITS, H. FRANK, H. MAYR, A. NEUHOLD* and D. GLOGER

Kardiologische Universitatsklinik
*Privatkrankenhaus Rudolfinerhaus Vienna, Austria

Received 23 May 1990; revised 23 November 1990; .

Correspondence Dr Sebastian Globits, University of Vienna. 2nd Clinic of Internal Medicine Dpt. of Cardiology. Wahringergürtel 18-20, A-1090 Vienns, Austria

Abstract

Thirty patients with aortic regurgitation and 10 controls were examined using an 0.5 T superconducting magnet with ECG gating. In each case a multislice-multiphase spinecho study in sagittal-coronal double angulated projection (four-chamber equivalent) was performed to assess left and right ventricular volumes, ejection fraction and regurgitation fraction. Additionally, a blood-flow sensitive cine-study (gradient echo, FAME) was performed to visualize direction and area of regurgitant jet. Magnetic resonance imaging (MRI) data were compared with quantitative and qualitative assessment of aortic regurgitation by angiography, Doppler and colour flow mapping. Using the FAME mode MRI, we were able to detect the regurgitant jet as an area of signal loss within the left ventricle in all patients; moderate correlation to jet area was determined by colourfiow mapping (R=0.60, P<0.001). Determination of left and right ventricular end-diastolic, end- systolic and stroke volumes by MRI revealed excellent correlation with invasive data (R = 0.94, p = 0.0001). With MRI regurgitant fraction (RF) could be calculated from the dfference between right and left ventricular stroke volumes, which showed good correlation with invasively determined RF (R = 0.91, P = 0.0001) and with qualitative Sellers' scoring (R = 0.70, P <0.001), respectively. Thus MRI provides the basis for noninvasive detection and quantification of aortic regurgitation.

Key Words: Magnetic resonance imaging • aortic regurgitation


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