Skip Navigation

European Heart Journal 1992 13(2):152-159;
Copyright © 1992 by the European Society of Cardiology.
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by VOELKER, W.
Right arrow Articles by KARSCH, K. R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by VOELKER, W.
Right arrow Articles by KARSCH, K. R.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1992 The European Society of Cardiology

Effect of heart rate on transmitral flow velocity profile and Doppler measurements of mitral valve area in patients with mitral stenosis

W. VOELKER, B. REGELE, H. DITTMANN, M. MAUSER, O. ICKRATH, K. M. SCHMID and K. R. KARSCH

Department of Cardiology Division of Medicine, Tuebingen University Germany

Received 26 September 1990; revised 19 March 1991; .

Correspondence Wolfram Voelker, MD, Department of Cardiology, Med. Klinik. Otfried Müller Str 10, 7400 Tübingen, Germany

Abstract

To study the effect of heart rate changes on Doppler measurements of mitral valve area atrial pacing was performed in 14 patients with mitral stenosis andsinus rhythm. Continuous wave Doppler and haemodynamic measurements were performed simultaneously at rest and during pacing-induced tachycardia. (1) Mitral valve area was determined using the conventional pressure half time method. (2) Additionally, mitral valve area was calculated with a combined Doppler and thermodilution technique according to the continuity equation. (3) Simultaneous invasive measurements were used for calculation of the mitral valve area according to the Gorlin formula. With increasing heart rate (69 ± 13–97 ± 15–114 ± 13 beats min–1) mitral valve area either determined by the continuity equation (1.0 ± 0.2–1.0 ± 0.3–1.1± 0.4 cm2) or the Gorlin formula (1.2±0.3–1.2±0.4–1.3±0.4cm2) remained constant. Both methods correlated closely not only at rest (r=0.88, SEE=0.11 cm2, P<0.001), but also during atrial pacing (first level: r=0.95, SEE=0.10 cm2, P<0.001 second level: r=0.95, SEE=0.13 cm2, P<0.001). In contrast, mitral valve area calculated according to the pressure half time method increased significantly during atrial pacing (1.0 ± 0.3–1.8 ±0.5 – 2.O ± 0.5 cm2). Mitral valve area determined either by the pressure half time method or the Gorlin formula correlated in patients with heart rates ≤80 beats min–1 (r=0.75, SEE = 0.15 cm2, p <0.01), while no significant correlation was found in patients with heart rates above 80 beats min–1.

Our conclusion is that while the pressure half time method progressively overestimates mitral valve area with increasing heart rate, the accuracy of the continuity equation method based on a combined Doppler/thermodilution technique is independent of heart rate changes in patients with mitral stenosis and sinus rhythm. This method is superior to the pressure half time method in patients with mitral stenosis and heart rates exceeding 80 beats min–1.

Key Words: Mitral stenosis • mitral valve area • pressure half time • continuity equation method • artrial pacing


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Eur J EchocardiogrHome page
N. Namboodiri, O. Shajeem, J. A. Tharakan, R. Sankarkumar, T. Titus, A. Valaparambil, S. Sivasankaran, K. M. Krishnamoorthy, S. P. Harikrishnan, and S. K. Dora
Doppler echocardiographic assessment of TTK Chitra prosthetic heart valve in the mitral position
Eur J Echocardiogr, September 1, 2008; 9(5): 599 - 604.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EchocardiogrHome page
N. Namboodiri, O. Shajeem, J. A. Tharakan, R. Sankarkumar, T. Titus, A. Valaparambil, S. Sivasankaran, K. M. Krishnamoorthy, S. P. Harikrishnan, and S. K. Dora
Doppler echocardiographic assessment of TTK Chitra prosthetic heart valve in the mitral position
Eur J Echocardiogr, March 18, 2008; (2008) jen030v1.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
D. Messika-Zeitoun, S. Fung Yiu, B. Cormier, B. Iung, C. Scott, A. Vahanian, A Jamil Tajik, and M. Enriquez-Sarano
Sequential assessment of mitral valve area during diastole using colour M-mode flow convergence analysis: new insights into mitral stenosis physiology
Eur. Heart J., July 1, 2003; 24(13): 1244 - 1253.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
J. C. Mohan, A. R. Patel, R. Passey, D. Gupta, M. Kumar, R. Arora, and N. G. Pandian
Is the mitral valve area flow-dependent in mitral stenosis?: A dobutamine stress echocardiographic study
J. Am. Coll. Cardiol., November 20, 2002; 40(10): 1809 - 1815.
[Abstract] [Full Text] [PDF]

Home page
 Journal of Diagnostic Medical SonographyHome page
C. M. Drake and C. Kraft
The Use of a Stand-of Device in High Pulse Repetition Frequeny Doppler Echocardiography
Journal of Diagnostic Medical Sonography, January 1, 1995; 11(1): 23 - 27.
[Abstract] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.