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European Heart Journal 1992 13(3):421-423;
Copyright © 1992 by the European Society of Cardiology.
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© 1992 The European Society of Cardiology

Sudden death during pregnancy in hypertrophic cardiomyopathy

F. PELLICCIA, C. CIANFROCCA, C. GAUDIO and A. REALE

Department of Cardiology, University of Rome ‘La Sapienza’ Rome, Italy

Received 11 December 1990; revised 11 March 1991; .

Corrrspondence Dr F. Pelliccia, via Tommaso Inghirami 85, 00179 Rome, Italy

Abstract

A 27-year-old asymptomatic woman became pregnant 6 months after a diagnosis of hypertrophic cardiomyopathy and was well until 28 weeks' gestation when she died suddenly while running upstairs. The potential pathophysiological mechanisms of sudden death during pregnancy in hypertrophic cardiomyopathy, as well as the diagnostic and therapeutic implications, are discussed.

Key Words: Hypertrophic cardiomyopathy • pregnancy • sudden death


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