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European Heart Journal 1992 13(6):781-786;
Copyright © 1992 by the European Society of Cardiology.
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© 1992 The European Society of Cardiology

Comparative long-term results of coronary angioplasty in single and multivessel disease

R. A. HENDERSON, C. RASKINO*, S. KARANI and E. SOWTON

Department of Cardiology, Guy's Hospital St Thomas Street, London SE1 9RT
*Department of Epidemiology and Population Sciences, Medical Statistics Unit, London School of Hygiene and Tropical Medicine Keppel Street, London WC1E7HT, U.K.

Received 11 January 1991; revised 24 July 1991; .

Correspondence- Dr Robert Henderson, Department of Cardiology, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT. U K

Abstract

The comparative long-term clinical results of coronary angioplasty in 448 patients with single-vessel and 451 patients with multivessel disease are reported. Clinical status was determined at census for 898 patients (99.9%). Actuarial survival at 5 years was 92. 7% for single-vessel and 85.6% for multivessel disease patients (relative risk 2.1). Patients with multivessel disease had higher rates of cardiac death and non-fatal myocardial infarction (relative risk 1.8), and coronary artery bypass surgery (relative risk 2.5) than patients with single-vessel disease. At follow-up 72.6% of single-vessel and 61.3% of multivessel disease patients had no angina and 43.3% and 35.8%, respectively, were taking no regular anti-anginal medication. Treatment by coronary angioplasty is associated with a good long-term prognosis, but survival and event-free survival rates are lower in patients with multivessel disease than in patients with single-vessel disease, even after correction for differences in other baseline characteristics.

Key Words: Coronary angioplasty • single vessel disease • multivessel disease • actuarial survival


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