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European Heart Journal 1992 13(6):840-843;
Copyright © 1992 by the European Society of Cardiology.
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© 1992 The European Society of Cardiology

Fatal haemostatic complications due to thrombolytic therapy in patients falsely diagnosed as acute myocardial infarction

U. H. ERIKSEN, H. ØLGAARD, J. INGERSLEV* and T. T. NIELSEN

Departments of Cardiology, Skejby University Hospital DK-8200 Århus N. Denmark
*Immunology, Skejby University Hospital DK-8200 Århus N. Denmark

Received 28 May 1991; revised 18 October 1991; .

Correspondence Ulrik Hedegaard Eriksen, MD, Department of Cardiology, Skejby University Hospital, DK-8200 Århus N. Denmark

Abstract

This report describes the fate of two young men wrongly treated with thrombolysis for suspected myocardial infarction. Both had electrocardiographic changes upon admission. Correct diagnosis of aortic dissection and haemorhagic pericarditis was obtained within a few hours, but due to the prolonged disturbance of haemostasis, appropriate therapy could not be instituted, and outcome was fatal for both patients. These cases underline the importance of rigid ST criteria, and procedures for neutralization of thrombolysis are proposed.

Key Words: Thrombolysis • myocardial infarction • aortic dissection • haemorhagic pericarditis • streptokinase


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