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European Heart Journal 1992 13(7):865-871;
Copyright © 1992 by the European Society of Cardiology.
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© 1992 The European Society of Cardiology

Characteristics of the ‘Metabolic Syndrome X’ in a cardiovascular low risk population in Crete

A. D. KOUTIS*, C. D. LIONIS*, Å. ISACSSON{dagger}, A. JAKOBSSON{dagger}, M. FIORETOS* and L. H. LINDHOLM{dagger},

*Dept. of Family Medicine and Social Medicine, Crete University Heraklion, Crete
{dagger}Health Sciences Centre, Lund University S-240 10 Dalby, Sweden

Received 17 May 1991; revised 30 September 1991; .

Correspondence: Lars H. Lindholm, Health Science Centre, Lund University, S-240 10 Dalby, Sweden.

Abstract

We have studied hypertension, obesity, diabetes and hypercholesterolaemia in those aged 45–79 years in the Cretan low risk population of Spili (n = 249; attendance 82%) to see if these conditions interacted in thesame way as previously described for high risk populations. Hypertension, diabetes, obesity, and hypercholesterolaemia were found to be at least as prevalent in Spili as in Sweden. Furthermore, the previously described ‘Metabolic Syndrome X’, with insulin resistance and hyper-insulinaemia as a common denominator also seemed to exist in the Spili population where patients with these conditions had higher insulin and C-peptide levels than normals. Our finding should be viewed against the low prevalence of past myocardial infarction in Cretan men from Spili reported by us and confirming the results of the Seven Countries Study.

Key Words: Diabetes • hypercholesterolaemia • hypertension • insulin • myocardial infarction • obesity


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