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European Heart Journal 1992 13(Supplement D):66-69; doi:10.1093/eurheartj/13.suppl_D.66
Copyright © 1992 by the European Society of Cardiology.
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© 1992 The European Society of Cardiology

Hypertension, left ventricular hypertrophy, ventricular arrhythmias and sudden death

F. H. Messerli and T. Grodzicki

Department of Internal Medicine, Section on Hypertension, Ochsner Clinic and Alton Ochsner Medical Foundation New Orleans, Louisiana, U.S.A.

Address for correspondence: Dr Messerli, Ochsner Clinic 1514 Jefferson Highway, New Orleans, Louisiana 70121, U.S.A.

LVH is a common sequela of arterial hypertension; it increases the risk of sudden death and other cardiovascular morbidity and mortality independent of arterial pressure and has been asociated with ventricular arrhythmias. Electro-physiological studies suggest a connection between ventricular arrhythmias in patients with LVH and sudden death. LVH can be reduced by specific antihyper tensive therapy, although not all drugs are equipolent in this regard A reduction in LVH has been shown to diminish ventricular ectopy. Preliminary findings suggest that a reduction of LVH and associated arrhythmias may reduce its inherent cardiovascular risk.

Key Words: Hypertension • left ventricular hypertrophy • ventricular arrhythmias • sudden death • antihypertensive therapy


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