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European Heart Journal 1993 14(4):576-578;
Copyright © 1993 by the European Society of Cardiology.
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© 1993 The European Society of Cardiology

Renovascular hypertension and coronary heart disease complicating essential thrombocythemia

D. O. ARNAR*, M. K. PÉTURSSON*,, E. JÓNMUNDSSON{dagger} and J. BJÖRNSDÓTTIR{ddagger}

*Department of Medicine, Landspitalinn, National University Hospital Reykjavik, Iceland
{dagger}Department of Radiology, Landspitalinn, National University Hospital Reykjavik Iceland
{ddagger}Department of Hematology, Landspitalinn, National University Hospital Reykjavik, Iceland

Received 16 June 1992; revised 29 October 1992; .

Correspondence: Magnús Karl Pétursson MD, Department of Medicine, Landspitalinn, National University Hospital, Reykjavik 101, Iceland.

Abstract

A 36-year-old male was evalued for treatment-resistant hypertension. A high platelet count 828. 109 l–1, led to the diagnosis of essential thrombocythemia (ET). Aorto-renal angiography revealed critical bilateral renal artery stenosis and coronary angiography showed three-vessel disease. Percutaneous transluminal renal angioplasty was only partially successful. The patient received a 12-week course of busulphan and subsequently the thrombocyte count decreased to 200. 109 l–1 Renal angiography 12 months later showed bilateral regression of the renal artery stenosis with lowering of the blood pressure to normal levels.

Key Words: Essential thrombocythemia • hypertension • regression of stenosis • renal artery stenosis


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