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European Heart Journal 1993 14(5):592-596;
Copyright © 1993 by the European Society of Cardiology.
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© 1993 The Europen Society of Cardiology

Heart volume and cardiovascular mortality

A 16 year follow-up study of 1984 healthy middle-aged men

L. SANDVIK, J. ERIKSSEN, E. THAULOW, G. ERIKSSEN, R. MUNDAL and T. AAKHUS

Department of Cardiology and Department of Radiology, University Hospital (Rikshospitalet) of Oslo Norway

Received 14 May 1992; revised 11 November 1992; .

Correspondence: Jan Erikssen, MD, Dept. of Med, Central Hospital of Akershus, N-1474 Nordbyhagen, Norway

Abstract

The possible association between heart size measured during a cardiovascular screening examination and cardiovascular mortality was studied in 1984 healthy men aged 40–59 years. At the 16-year follow-up 278 had died, 150 from cardiovascular diseases. Cardiovascular mortality was 2.2 times higher among the 122 men with heart size ≥ 500 ml. m–2 than among those with heart size < 500 ml .m–2. This association was, however, exclusively confined to men with physical fitness below median in whom the corresponding mortality ratio was 4.6 (95% confidence interval 2.5–8.4; P<0.001) after adjustment for age, smoking, cholesterol, blood pressure and heart rale. Heart size measurements from routine chest X-rays is fast, easy, inexpensive and appears to provide valuable, independent screening information in healthy, middle-aged men.

Key Words: Healthy men • heart volume • physical fitness • cardiovascular mortality


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