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European Heart Journal 1993 14(9):1289-1291;
Copyright © 1993 by the European Society of Cardiology.
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© 1993 The Europen Society of Cardiology

Ondine's curse and neurally mediated syncope — a new and important association

J. O'SULLIVAN*,, A. J. COTTRELL{dagger} and C. WREN*

*Department of Paediatric Cardiology, Freeman Hospital Newcastle upon Tyne NE7 7DN, U.K.
{dagger}Department of Paediatrics, Bishop Auckland General Hospital Bishop Auckland, Co Durham, U.K.

Received 21 December 1992; revised 29 March 1993; .

Correspondence: John O'Sullivan, Department of Paediatric Cardiology, Freeman Hospital, Newcastle upon Tyne NE7 7DN, U.K.

Abstract

A 6-year-old boy with congenital central hypoventilation syndrome (Ondine's curse) presented with presyncope. Investigation revealed a diagnosis of neurally mediated syncope. This previously unreported association provides strong evidence that autonomic dysfunction is implicated in both these conditions.

Key Words: Syncope • hypoventilation • autonomic nervous system


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