Copyright © 1993 by the European Society of Cardiology.
© 1993 The European Society of Cardiology
The hibernating myocardium in ischaemia and congestive heart failure
Griffith Center, University of Southern California School of Medicine Los Angeles, California, U.S.A.
Correspondence: Shahbudin H. Rahimtoola, MD. University of Southern California, 2025 Zonal Avenue, Los Angeles, CA 90033. U.S.A.
Hibernating myocardium refers to the presence of persistent myocardial and left ventricular dysfunction at rest due to reduced coronary blood flow that can be partially or completely restored to normal by myocardial revascularization. An increasing amount of data show it is most likely a downgrading of cardiac function so that blood flow and myocardial function are once again in a state of equilibrium.
It has been demonstrated to occur in patients with unstable angina, chronic stable angina, acute myocardial infarction and in left ventricular dysfunction and/or congestive heart failure. Salvage of this viable myocardium by successful revascularization improves left ventricular dysfunction and probably also patient survival.
Therefore, diagnosis of hibernating myocardium is important because it does not render left ventricular dysfunction a necessary contraindication to revascularization, nor does it leave the patient with chronic heart failure a candidate only for cardiac transplantation. Instead, these patients should have complete revascularization by coronary bypass surgery/percutaneous transluminal coronary angioplasty as soon as possible.
Key Words: Hibernating myocardium • viable myocardium • angina • acute myocardial infarction • congestive heart failure • left ventricular dysfunction • cardiac transplantation • coronary bypass surgery • percutaneous transluminal coronary angioplasty
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