Copyright © 1994 by the European Society of Cardiology.
© 1994 The European Society of Cardiology
Chrome congestive heart failure
Abnormalities of left ventricular filling in patients with coronary artery disease: assessment by colour M-mode Doppler technique


*Medical Department B, The National Hospital Oslo, Norway
Department of Radiology, Rikshospitalet, The National Hospital Oslo, Norway
Institute of Biomedical Engineering, University of Trondheim Trondheim, Norway
Received 7 June 1993; revised 7 October 1993; .
Correspondence: Dr Marie Stugaard, Medical Department B. Rikshospitalet, The National Hospital, N-0027 Oslo, Norway
Abstract
In 54 healthy individuals and 107 patients with coronary artery disease, intraventricular early filling velocities were recorded by colour M-mode Doppler. The time difference between the occurrence of peak velocity in the apical region and at the mitral tip was calculated, and normalized by dividing it by the mitral to apical distance. Transmitral velocities were determined by the single pulsed Doppler technique. The patients were divided into groups according to systolic function as assessed by left ventriculography.
The normalized time difference was similar in the reference group (12±8 ms. cm1) and the patient group with no electrocardiographical signs of previous infarction and normal ventriculography (16±16 ms. cm1) It increased significantly in the group with infarction and/or regional systolic dysfunction (43±21 ms. cm1), and a further increase was present in the group with severely impaired ventricles (53±14 ms. cm1). The ratio between peak early and late traiismitral velocity fell significantly in the group with infarction and/or regional systolic dysfunction, but was normalized in the group with severely impaired ventricles.
Colour M-mode Doppler shows that apical filling is delayed in patients with injured left ventricles due to coronary artery disease. This delay increases with progression of ventricular injury. The technique may be an important addition to transmitral pulsed Doppler in assessing left ventricular filling.
Key Words: Computer analysis diastole echocardiography filling delay peak velocity
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