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European Heart Journal 1994 15(Supplement C):49-51; doi:10.1093/eurheartj/15.suppl_C.49
Copyright © 1994 by the European Society of Cardiology.
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© 1994 The European Society of Cardiology

Cardiac Late Potentials for Diagnosis in Heart Disease

J. Brachmann, T. Hilbel, M. Schweizer and W. KÜbler

Medizintsche Universitätsklinik Heidelberg, Germany

Correspondence: PD Dr J. Brachmann. Medizinische Universitätsklinik, Dept. of Cardiology, Bergheimerstr. 58-69115 Heidelberg, Germany

In recent years abundant information has been obtained about the relationship of heart disease and cardiac late potentials. Non-invasive recordings of ventricular late potentials are useful in risk stratification of various clinical conditions, in particular, in patients following myocardial infarction. Here a close correlation has been established between cardiac late potentials and spontaneous or induced sustained ventricular tachycardias using programmed electrical stimulation. Cardiac late potentials also appear to be associated with arrhythmic events in patients with cardiomyopathies, and following unsuccessfu1 antitachycardia surgery. Furthermore, recording of abnormal late potentials are associated both with acute rejection after cardiac transplantation and unsuccessful thrombolytic therapy after myocardial infarction. Interestingly, antiarrhytmic drugs have no clear effect on cardiac late potentials.

Key Words: Cardiac late potential • signal averaged ECG • diagnosis of heart disease • ventricular arrhythmia • sudden cardiac death • antiarrhythmic drugs • thrombolytic therapy • cardiac transplantation


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