Skip Navigation

European Heart Journal 1995 16(2):218-222;
Copyright © 1995 by the European Society of Cardiology.
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by GRIMM, W.
Right arrow Articles by MARCHLINSKI, F. E.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by GRIMM, W.
Right arrow Articles by MARCHLINSKI, F. E.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1995 The European Society of Cardiology

Shock occurrence and survival in 49 patients with idiopathic dilated cardiomyopathy and an implantable cardioverter-defibrillator

W. GRIMM and F. E. MARCHLINSKI*

Clinical Electrophysiology Laboratory, Cardiology Division, Department of Medicine, Hospital of the University of Pennsylvania Philadelphia, PA, U.S.A
*Philadelphia Heart Institute (Sidney Kimmel Cardiovascular Research Center) Philadelphia, PA, U.S.A

Received 20 September 1993; revised 14 June 1994; accepted 10 August 1994.

Correspondence: Wolfram Grimm, MD, Philipps-University Marburg. Zentrum für Innere Medizin — Abt Kardiologie, BaldingerstraBe, 35033 Marburg, Germany

Abstract

To determine shock occurrence and survival, 49 patients with idiopathic dilated cardiomyopathy presenting with cardiac arrest (82%), syncope (12%) or ventricular tachycardia without syncope (6%) were followed for 28 ±28 months after cardioverter-defibrillator (ICD) implant according to the intention to treat principle. Using the Kaplan-Meier method, the actuarial incidence for any spontaneous shocks was 20%, 58%, and 77%, and the incidence of appropriate shocks was 16%, 49%, and 72% at 1, 3, and 5 years of follow-up, respectively. Only two of 49 study patients (4%) with an active ICD died suddenly during follow-up. Another two patients, however, with an inactive device died suddenly, resulting in a sudden death rate of 2% per year with an active ICD, and 5% per year, according to the intention to treat principle. The incidence of cardiac death from any cause was 8%, 25%, and 35%, and the incidence of total mortality was 14%, 39%, and 49% during 1, 3, and 5 years of follow-up, respectively. There was no difference in the Kaplan-Meier survival curves for shocked vs non-shocked patients. Thus, in this selected patient population with idiopathic dilated cardiomyopathy the majority of patients received ‘appropriate’ shocks during follow-up, and the sudden death rate with active ICD is low.

Key Words: Idiopathic dilated cardiomyopathy • implantable cardioverter-defibrillator • sudden cardiac death • spontaneous shocks


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J Am Coll CardiolHome page
S. A. Strickberger, D. W. Benson, I. Biaggioni, D. J. Callans, M. I. Cohen, K. A. Ellenbogen, A. E. Epstein, P. Friedman, J. Goldberger, P. A. Heidenreich, et al.
AHA/ACCF Scientific Statement on the Evaluation of Syncope: From the American Heart Association Councils on Clinical Cardiology, Cardiovascular Nursing, Cardiovascular Disease in the Young, and Stroke, and the Quality of Care and Outcomes Research Interdisciplinary Working Group; and the American College of Cardiology Foundation In Collaboration With the Heart Rhythm Society
J. Am. Coll. Cardiol., January 17, 2006; 47(2): 473 - 484.
[Full Text] [PDF]

Home page
 CirculationHome page
S. A. Strickberger, D. W. Benson, I. Biaggioni, D. J. Callans, M. I. Cohen, K. A. Ellenbogen, A. E. Epstein, P. Friedman, J. Goldberger, P. A. Heidenreich, et al.
AHA/ACCF Scientific Statement on the Evaluation of Syncope: From the American Heart Association Councils on Clinical Cardiology, Cardiovascular Nursing, Cardiovascular Disease in the Young, and Stroke, and the Quality of Care and Outcomes Research Interdisciplinary Working Group; and the American College of Cardiology Foundation: In Collaboration With the Heart Rhythm Society: Endorsed by the American Autonomic Society
Circulation, January 17, 2006; 113(2): 316 - 327.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
W. Grimm, J.u. Hoffmann, H.-H. Muller, and B. Maisch
Implantable defibrillator event rates in patients with idiopathic dilated cardiomyopathy, nonsustained ventricular tachycardia on Holter and a left ventricular ejection fraction below 30%
J. Am. Coll. Cardiol., March 6, 2002; 39(5): 780 - 787.
[Abstract] [Full Text] [PDF]

Home page
 Cardiovasc ResHome page
G. Gronefeld and S. H Hohnloser
What do implantable cardioverter/defibrillators teach us about the mechanisms of sudden cardiac death?
Cardiovasc Res, May 1, 2001; 50(2): 232 - 241.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
B. P. Knight, R. Goyal, F. Pelosi, M. Flemming, L. Horwood, F. Morady, and S. A. Strickberger
Outcome of patients with nonischemic dilated cardiomyopathy and unexplained syncope treated with an implantable defibrillator
J. Am. Coll. Cardiol., June 1, 1999; 33(7): 1964 - 1970.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.