Copyright © 1995 by the European Society of Cardiology.
© 1995 The European Society of Cardiology
Reversal of autonomic derangements by physical training in chronic heart failure assessed by heart rate variability
Division of Cardiology, Department of Medicine, Helsinki University Central Hospital Helsinki, Finland
revised 24 August 1994; accepted 22 September 1994.
Abstract
Decreased heart rate variability has been associated with chronic congestive heart failure (CHF). We evaluated the effect of physical training on heart rate variability in 20 patients with CHF (NYHA class II-III) randomized to training (n = 8) and control (n = 12) groups. The training group underwent 3 months of physical training, by exercising on a bicycle ergometer for 30 min three times a week at a load corresponding to 50–60% of their peak oxygen consumption. Heart rate variability was assessed from 20-h ambulatory ECG recordings in the frequency domain, determined by high (0.15–0–40 Hz), low (0.04–0.15 Hz) and very low frequency (0.008–0.04 Hz) components. The high frequency component increased by 22–55% in the training group during the day (P=0.0001) but not at night. The increase was seen during both sedentary and active periods. The low frequency/high frequency ratio attenuated in the training group during the day (P=0.05) whereas an increase was seen in the control group throughout the day (P=0.0003). Training lengthened the exercise duration by 71% at a submaximal workload (P=0.01) and tended to increase the peak oxygen consumption by 15% (P = 0.09). These remained unchanged in the control group. In conclusion, physical training, which improves exercise capacity, ameliorates the autonomic derangement in CHF by increasing the parasympathetically mediated component of heart rate variability. It may thus influence favourably the prognosis of the disease.
Key Words: Heart rate variability • autonomic nervous system • congestive heart failure • physical training
CiteULike 
Connotea 
Del.icio.us What's this?
This article has been cited by other articles:
|
|
 |
|
  G. E. Billman Cardiac autonomic neural remodeling and susceptibility to sudden cardiac death: effect of endurance exercise training Am J Physiol Heart Circ Physiol, October 1, 2009; 297(4): H1171 - H1193. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. A. Hunt, W. T. Abraham, M. H. Chin, A. M. Feldman, G. S. Francis, T. G. Ganiats, M. Jessup, M. A. Konstam, D. M. Mancini, K. Michl, et al. 2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines Developed in Collaboration With the International Society for Heart and Lung Transplantation J. Am. Coll. Cardiol., April 14, 2009; 53(15): e1 - e90. [Full Text] [PDF]
|
|
|
|
 |
|
 2005 WRITING COMMITTEE MEMBERS, S. A. Hunt, W. T. Abraham, M. H. Chin, A. M. Feldman, G. S. Francis, T. G. Ganiats, M. Jessup, M. A. Konstam, D. M. Mancini, et al. 2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines: Developed in Collaboration With the International Society for Heart and Lung Transplantation Circulation, April 14, 2009; 119(14): e391 - e479. [Full Text] [PDF]
|
|
|
|
 |
|
 G. Gardenghi, M. U. P.B. Rondon, A. M. F.W. Braga, M. I. Scanavacca, C. E. Negrao, E. Sosa, and D. T. Hachul The effects of exercise training on arterial baroreflex sensitivity in neurally mediated syncope patients Eur. Heart J., November 2, 2007; 28(22): 2749 - 2755. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Fraga, F. G. Franco, F. Roveda, L. N.J. de Matos, A. M.F.W. Braga, M. U.P.B. Rondon, D. R. Rotta, P. C. Brum, A. C.P. Barretto, H. R. Middlekauff, et al. Exercise training reduces sympathetic nerve activity in heart failure patients treated with carvedilol Eur J Heart Fail, June 1, 2007; 9(6-7): 630 - 636. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. A.F. van Tol, R. J. Huijsmans, D. W. Kroon, M. Schothorst, and G. Kwakkel Effects of exercise training on cardiac performance, exercise capacity and quality of life in patients with heart failure: A meta-analysis Eur J Heart Fail, December 1, 2006; 8(8): 841 - 850. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. L. Lujan, S. L. Britton, L. G. Koch, and S. E. DiCarlo Reduced susceptibility to ventricular tachyarrhythmias in rats selectively bred for high aerobic capacity Am J Physiol Heart Circ Physiol, December 1, 2006; 291(6): H2933 - H2941. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. L. Collins, A. M. Loka, and S. E. DiCarlo Daily exercise-induced cardioprotection is associated with changes in calcium regulatory proteins in hypertensive rats Am J Physiol Heart Circ Physiol, February 1, 2005; 288(2): H532 - H540. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Roveda, H. R. Middlekauff, M. U. P. B. Rondon, S. F. Reis, M. Souza, L. Nastari, A. C. P. Barretto, E. M. Krieger, and C. E. Negrao The effects of exercise training on sympathetic neural activation in advanced heart failure: A randomized controlled trial J. Am. Coll. Cardiol., September 3, 2003; 42(5): 854 - 860. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 K. J. Stewart, D. Badenhop, P. H. Brubaker, S. J. Keteyian, and M. King Cardiac Rehabilitation Following Percutaneous Revascularization, Heart Transplant, Heart Valve Surgery, and for Chronic Heart Failure Chest, June 1, 2003; 123(6): 2104 - 2111. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Pietila, K. Malminiemi, R. Vesalainen, T. Jartti, M. Teras, K. Nagren, P. Lehikoinen, and L.-M. Voipio-Pulkki Exercise Training in Chronic Heart Failure: Beneficial Effects on Cardiac 11C-Hydroxyephedrine PET, Autonomic Nervous Control, and Ventricular Repolarization J. Nucl. Med., June 1, 2002; 43(6): 773 - 779. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. E. Billman Aerobic exercise conditioning: a nonpharmacological antiarrhythmic intervention J Appl Physiol, February 1, 2002; 92(2): 446 - 454. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A.I Larsen, T Aarsland, M Kristiansen, A Haugland, and K Dickstein Assessing the effect of exercise training in men with heart failure. Comparison of maximal, submaximal and endurance exercise protocols Eur. Heart J., April 2, 2001; 22(8): 684 - 692. [Abstract] [PDF]
|
|
|
|
|
|
Recommendations for exercise training in chronic heart failure patients Eur. Heart J., January 2, 2001; 22(2): 125 - 135. [PDF]
|
|
|
|
 |
|
 C. F. Notarius and J. S. Floras Limitations of the use of spectral analysis of heart rate variability for the estimation of cardiac sympathetic activity in heart failure Europace, January 1, 2001; 3(1): 29 - 38. [Abstract] [PDF]
|
|
|
|
 |
|
 R. Humphrey and R. Arena Surgical Innovations for Chronic Heart Failure in the Context of Cardiopulmonary Rehabilitation Physical Therapy, January 1, 2000; 80(1): 61 - 69. [Full Text] [PDF]
|
|
|
|
|
|
K. Meyer Exercise training in chronic heart failure: is it really safe? Eur. Heart J., June 2, 1999; 20(12): 851 - 853. [PDF]
|
|
|
|
|
|
R.P. Wielenga, I.A. Huisveld, E. Bol, P.H.J.M. Dunselman, R.A.M. Erdman, M.R.P. Baselier, and W.L. Mosterd Safety and effects of physical training in chronic heart failure. Results of the Chronic Heart Failure and Graded Exercise study (CHANGE): (CHANGE) Eur. Heart J., June 2, 1999; 20(12): 872 - 879. [Abstract] [PDF]
|
|
|
|
|
|
A. J. S. Coats Exercise Training for Heart Failure : Coming of Age Circulation, March 9, 1999; 99(9): 1138 - 1140. [Full Text] [PDF]
|
|