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European Heart Journal 1995 16(Supplement B):122-125; doi:10.1093/eurheartj/16.suppl_B.122
Copyright © 1995 by the European Society of Cardiology.
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© 1995 The European Society of Cardiology

The prophylaxis of infective endocarditis: Current practices in France

N. Danchin

Service de Cardiologie A, Chu Nancy-Brabois 54500 Vandoeuvre-lès-Nancy, France

Correspondence: Nicolas Danchin, Service de Cardiologie A, Chu Nancy-Brabois, 54500 Vandoeuvre-lès-Nancy, France.

Over the last 10 years, the French Federation of Cardiology has circulated recommendations regarding the use of chemoprophylaxis in patients at risk for infective endocarditis. A national survey conducted in 1991, however, showed that the vast majority of both general practitioners and dentists were unaware of these recommendations. Therefore, a Consensus Conference was convened in 1992, with the object of defining and circulating new guidelines which were to be as practical as possible, for the prophylaxis of infective endocarditis. The Consensus Conference first defined which categories of subjects were at risk for infective endocarditis and which types of procedures were potential causes of endocarditis. The second task of the Conference was to determine recommendations for chemoprophylaxis before procedures at risk. For ambulatory dental procedures, a single oral dose of 3 g of amoxicillin administered in the hour preceding the procedure was recommended. Additional recommendations were made for subjects with an allergy to penicillin, for procedures requiring general anaesthesia or for urologic or digestive tract procedures. These recommendations were printed on credit-card format cards and distributed to all practising cardiologists, who were encouraged to give each of their patients at risk a personal card bearing his/her name and the type of heart condition at risk. It is hoped that these measures to both simplify the prophylactic antibiotic regimen and circulate the recommendations from the Consensus Conference may reduce the incidence of this still severe disease.

Key Words: Infective endocarditis • prophylaxis • antibiotic therapy • valvular heart disease


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