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European Heart Journal 1995 16(Supplement I):104-114; doi:10.1093/eurheartj/16.suppl_I.104
Copyright © 1995 by the European Society of Cardiology.
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© 1995 The European Society of Cardiology

New invasive techniques of assessment of the physiological significance of coronary stenoses in humans

C. Di Mario, R. Gil*, R. Krams{dagger}, P. J. De Feyter and W. Serruys

Intracoronary Imaging Laboratory, Cardiac Catheterization Laboratory Rotterdam, The Netherlands
{dagger} Catheterization Laboratory, Division of Cardiology, Thoraxcenter, Erasmus University Rotterdam, The Netherlands

Correspondence: Dr Patrick Serruys MD, PhD, Cardiac Catheterization Laboratory, Div. Cardiology, Thoraxcenter. BD 416. Erasmus University, P.O. Box 1738, 3015 GD Rotterdam, The Netherlands

Pressure and flow velocity can be measured distal to coronary stenoses by means of miniaturized sensors with guidewire technology. This is an alternative non-invasive method of assessing functional coronary stenosis severity, applicable for the intermediate stenoses and for the results of coronary interventions. The complexity of the coronary circulation, however, limits the possibility of establishing simple cut-off criteria to identify flow-limiting stenoses. In this paper we review advan tages and limitations of the different pressure and velocity indices and their application in different clinical settings.

Key Words: Coronary flow • Doppler velocimetry

* Dr R. Gil is the recipient of a Training Fellowship 1994 of the European Society of Cardiology.


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