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European Heart Journal 1996 17(2):222-229;
Copyright © 1996 by the European Society of Cardiology.
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© 1996 The European Society of Cardiology

Dobutamine stress echocardiography after coronary artery bypass grafting

Transthoracic vs biplane transoesophageal imaging

R. Hoffmann, H. Lethen, F. Falter, F. A. Flachskampf and P. Hanrath

Medical Clinic I Klinikum RWTH Aachen Germany

Received 2 January 1995; accepted 11 July 1995.

Correspondence: Rainer Hoffmann, MD, Medical Clinic I, Klinikum RWTH Aachen, Pauwelsstrasse, 52057 Aachen, Germany

Abstract

Graft failure or progressive native vessel disease can be a serious problem after coronary artery bypass grafting. However, because of poor image quality it may be difficult to evaluate these patients by transthoracic stress echocardi ography. The purpose of this study, therefore, was to evaluate the effectiveness of dobutamine stress echocardi ography in the detection of myocardial territories with compromised vascular supply (due to either an obstnicted native vessel without graft, an obstructed graft, or a native vessel obstructed distal to bypass graft insertion with ≤50% luminal diameter reduction on angiography) after coronary artery bypass grafting and to determine addi tional information obtained by biplane transoesophageal stress echocardiography.

Sixty patients (54 men, mean age 59±85 years) who had undergone coronary bypass grafting (total number of graft vessels 198) were evaluated from 6 months to 14 years (mean 6·2 years) after surgery. Transthoracic dobutamine stress echocardiography, biplane transoesophageal dobutamine stress echo, and coronary angiography were performed and evaluated by independent examiners. An infusion of dobutamine up to a maximum of 40 µg . kg–1. mm–1 was administered, and additional atropine (0·25–1·0 mg) was given if 85% of age-predicted maximal heart rate was not reached. Biplane transoesopha geal echocardiography was performed in the transgastric short-axis view as well as transoesophageal 4- and 2-chamber views, allowing division of the left ventricle into a 14-segment scheme. Wall motion abnormalities induced with dobutamine stress were used to predict regional vas cular insufficiency. A 4-point scale, ranging from ‘excellent’ (I) to ‘impossible’ (4) was used to assess each system's ability to evaluate all left ventricular segments.

Forty-five patients, of whom 35 were identified by trans thoracic echocardiography (sensitivity 78%), had at least one territory with a compromised vascular supply. In 15 patients, the vascular supply was uncompromised, with 13 showing no wall motion abnormalities inducible by trans thoracic echocardiography (specificity 86%). However, biplane transoesophageal echocardiography had a higher sensitivity and specificity than transthoracic echocardiogra phy in detecting compromised vascular supply, 93% and 93%, respectively. The former system correctly classified the vascu lar supplies in 113 of 120 vascular territories (94%), according to whether they were compromised or uncompromised. This was significantly more (P<0·05) than by classification with transthoracic dobutamine echocardiography, by which sys tem only 102 of the 120 vascular territories were correctly assessed (85%). Compared with the conventional transgastric monoplane short-axis view, examination using three different views via a biplane probe results in a higher sensitivity (93% vs 84%). Assessed on a 4-point scale, the ability to evaluate all left ventricular segments was 2·3 ± 0·7 (mean ± SD) for transthoracic echocardiography and l ± 0·7 (P<0·0l) for biplane transoesophageal echocardiography.

After coronary artery bypass grafting transthoracic dob utamine stress echocardiography has acceptable accuracy in the detection of regional vascular insufficiency. However, this accuracy can be improved using the higher image quality of transoesophageal echocardiography, combined with the advantages of several different views obtained by biplane transoesophageal echocardiography.

Key Words: Biplane transoesophageal echocardiography • coronary artery bypass grafting • dobutamine echocardiography


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