Skip Navigation

European Heart Journal 1997 18(10):1599-1605;
Copyright © 1997 by the European Society of Cardiology.
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Coletta, C.
Right arrow Articles by Ceci, V.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Coletta, C.
Right arrow Articles by Ceci, V.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1997 The European Society of Cardiology

Prognostic value of left ventricular volume response during dobutamine stress echocardiography

C. Coletta, A. Galati, R. Ricci, A. Sestili, G. Guagnozzi, F. Re and V. Ceci

Department of Cardiology, S. Spirito Hospital Rome, Italy

revised 11 April 1997; accepted 25 April 1997.

Correspondence: Claudio Coletta, via Annia 26 00184 Rome, Italy

Abstract

AIMS: An abnormal left ventricular volume response during dobutamine echocardiography identified patients with severe coronary artery disease. The aim of the study was to assess the prognostic value of left ventricular volume changes during dobutamine stress echocardiography in 136 patients.

MEHTODS AND RESULTS: Endpoints were defined as spontaneous cardiac events at follow-up. Left ventricular end-diastolic and end-systolic volume changes (abnormal response: >10% and >20> decrease, respectively) were compared with other clinical and stress test variables. During 18±7 months of follow-up, 31 cardiac events occurred: 12 hard events (cardiac death [n=6 myocardial infarction [n=6]) and 19 soft events (unstable angina [n=16] congestive heart failure [n=3] End-diastolic volume response (P=0·006), diabetes (P=0·008), inducible wall motion abnormalities (P=0·024), end-systolic volume response (P=0·039) and inducible angina (P=0·038) were related to a greater likelihood of cardiac events. The Cox regression analysis revealed end-diastolic volume response (odds ratio: 3·0; CI 1·44–6·32) and diabetes (odds ratio: 2·7; CI 1·28–5·69) to be independent predictors of spontaneous cardiac events. Diabetes (odds ratio: 4·0; CI 1·26–12·80) and >40% baseline ejection fraction (odds ratio: 2·21; CI 1·14–4·29) were independent predictors of hard events.

CONCLUSIONS: An abnormal end-diastolic volume response during dobutamine stress echocardiography identifies patients with an unfavourable outcome; they should be considered for more accurate prognostic stratification.

Key Words: Dobutamine echocardiography • left ventricular volume • prognosis


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Eur Heart JHome page
N. Chaowalit, R. B. McCully, M. J. Callahan, F. Mookadam, K. R. Bailey, and P. A. Pellikka
Outcomes after normal dobutamine stress echocardiography and predictors of adverse events: long-term follow-up of 3014 patients
Eur. Heart J., December 2, 2006; 27(24): 3039 - 3044.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EchocardiogrHome page
A. D'Andrea, S. Severino, P. Caso, B. Liccardo, A. Forni, A. Fusco, R. Lo Piccolo, M. Scherillo, N. Mininni, and R. Calabro
Prognostic value of supine bicycle exercise stress echocardiography in patients with known or suspected coronary artery disease
Eur J Echocardiogr, August 1, 2005; 6(4): 271 - 279.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EchocardiogrHome page
A D'Andrea, S Severino, P Caso, L De Simone, B Liccardo, A Forni, M Pascotto, G Di Salvo, M Scherillo, N Mininni, et al.
Prognostic value of pharmacological stress echocardiography in diabetic patients
Eur J Echocardiogr, September 1, 2003; 4(3): 202 - 208.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.