Skip Navigation

European Heart Journal 1997 18(11):1823-1828;
Copyright © 1997 by the European Society of Cardiology.
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Douard, H.
Right arrow Articles by Broustet, J. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Douard, H.
Right arrow Articles by Broustet, J. P.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1997 The European Society of Cardiology

Predictive factors of maximal aerobic capacity after cardiac transplantation

H. Douard, E. Parrens, M. A. Billes, L. Labbe, E. Baudet and J. P. Broustet

Hôpital Cardiologique du Haut Lévèque Pessac, France

Received 3 April 1997; accepted 11 April 1997.

Correspondence: H. Douard, Hôpital Cardiologique du Haut Lévèque, 33604 Pessac, France

Abstract

Exercise capacity in cardiac transplanted patients has been reported to remain decreased in some studies; however, functional results after transplantation may vary, ranging from modest to spectacular improvement. The aim of the study was to quantify exercise capacity in a large series of transplanted patients and to search for factor predictive of a good functional result

Eighty-five patients (mean 52·1±11·8 years) underwent exercise testing with respiratory gas exchange measurements 1 to 100 months after transplantation. Mean performance was 112·4±33 W with a peak Vo2 of 21·1±6 ml. min–1. kg–1. Heart rate was 103±14 at rest, reaching 142±22 beats. min–1 at the end of exercising.

In univariate analysis, maximal or submaximal aerobic capacity parameters were strongly correlated with chronotropic reserve (r=0·63; P<0·001) without correlation with cold ischaemic time, number of rejection episodes or right bundle branch block. In multiple regression analysis, chronotropic reserve, time from transplantation, age of donor and age of patient were proved to be the variables best correlated with peak Vo2.

Our study confirms the persistance of a large decrease in aerobic functional capacity despite cardiac transplantation; limited exercise capacity does not improve over time, and is limited not only by the patient's age but by that of the donor, and especially by chronotropic reserve.

Key Words: Cardiac transplantation • exercise testing • heart-rate • gas exchange analysis


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
A. Houssiere, M. Gujic, G. Deboeck, A. Ciarka, R. Naeije, and P. van de Borne
Increased metaboreflex activity is related to exercise intolerance in heart transplant patients
Am J Physiol Heart Circ Physiol, December 1, 2007; 293(6): H3699 - H3706.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
J. Myers, O. Geiran, S. Simonsen, A. Ghuyoumi, and L. Gullestad
Clinical and Exercise Test Determinants of Survival After Cardiac Transplantation
Chest, November 1, 2003; 124(5): 2000 - 2005.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
R. Ewert, R. Wensel, L. Bruch, S. Mutze, U. Bauer, M. Plauth, and F.-X. Kleber
Relationship Between Impaired Pulmonary Diffusion and Cardiopulmonary Exercise Capacity After Heart Transplantation
Chest, April 1, 2000; 117(4): 968 - 975.
[Abstract] [Full Text] [PDF]

Home page
 HeartHome page
H Omran, W Jung, R Rabahieh, P Wirtz, H Becher, S Illien, R Schimpf, and B Lüderitz
Imaging of thrombi and assessment of left atrial appendage function: a prospective study comparing transthoracic and transoesophageal echocardiography
Heart, February 1, 1999; 81(2): 192 - 198.
[Abstract] [Full Text]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.