Copyright © 1997 by the European Society of Cardiology.
© 1997 The European Society of Cardiology
Evaluation and prognostic significance of left ventricular diastolic function assessed by Doppler echocardiography in the early phase of a first acute myocardial infarction
Section of Cardiology, Department of Medicine, Haderslev Hospital and Department of Cardiology, University Hospital Aarhus Amtssygehus, Denmark
Received 13 May 1997; accepted 16 May 1997.
Correspondence: Steen Hvitfeldt Poulsen, MD, Ribelandevej 95, Department of Medicine, Haderslev Hospital, 6100 Haderslev, Denmark
Abstract
AIM: To study the prognostic significance of left ventricular diastolic function evaluated by transmitral and pulmonary venous flow velocities obtained in the early phase of a first acute myocardial infarction in relation to later development of congestive heart failure.
METHODS: Pulsed Doppler echocardiography of transmitral and pulmonary venous flow was assessed in 65 consecutive patients with a first myocardial infarction within 1 h of arrival in the coronary care unit.
RESULTS: A univariate regression analysis identified age, left ventricular ejection fraction 
45%, mitral E deceleration time 130 ms, E/A ratio >1·5, peak pulmonary venous atrial flow velocity 
30 cm . s–1 and a difference between mitral and pulmonary venous atrial flow duration >0 ms as variables significantly related to the development of congestive heart failure. However, in a multivariate analysis only mitral E deceleration time 130 ms and age were significant independent variables related to the development of congestive heart failure during the first week following a first acute myocardial infarction.
CONCLUSION: Assessment of left ventricular diastolic function complements measurements of systolic function in the evaluation of cardiac function, and mitral deceleration 130 ms best identifies patients at risk of development of congestive heart failure following acute myocardial infarction.
Key Words: Prognosis • diastolic function • Doppler echocardiography • MI
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