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European Heart Journal 1998 19(10):1583-1588; doi:10.1053/euhj.1998.1091
Copyright © 1998 by the European Society of Cardiology.
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Left ventricular ejection fraction in children measured by three-dimensional echocardiography using a new transthoracic integrated 3D-probe

A comparison with equilibrium radionuclide angiography

P. Acaraf1, C. Maunouryb, T. Antoniettib, D. Bonneta, D. Sidia and J. Kachanera

a Services de Cardiologie Pédiatrique, Hôpital Necker/Enfants-malades, Paris, France
b Services de Médecine Nucléaire, Hôpital Necker/Enfants-malades, Paris, France

accepted March 30, 1998

Background Three-dimensional echocardiography allows calculation of left ventricular ejection fraction without geometric assumption on the ventricular shape. Our aim was to validate this technique in a paediatric population with distorted ventricles.

Methods Twenty-one patients aged 6 months to 17 years underwent equilibrium radionuclide angiography and three-dimensional echocardiography. Fourteen patients had dilated cardiomyopathy and seven had univentricular hearts. A new, easy to handle, transthoracic rotational probe was used and motion artefacts were limited during the rotation (3° intervals with ECG and respiratory gating). Left ventricular volumes and ejection fraction were calculated using the Simpson’s rule with 12 slices.

Results Three-dimensional echocardiography correlated well with equilibrium radionuclide angiography for ejection fraction measurement (r=0·90; the mean difference between the two methods being 3·8±6%). Intra-observer and inter-observer variabilities for 3D echocardiography were 2·4% and 4·5%.

Conclusions Three-dimensional echocardiography is an accurate, non-invasive, and reproducible methods to measure left ventricular ejection fraction in children.

Key Words: Three-dimensional echocardiography • left ventricular ejection fraction • children

f1 Correspondence: Dr Philippe Acar, Service de Cardiologie Pédiatrique, Hôpital Necker Enfants-malades 149, rue de Sèvres 75743 Paris cedex 15, France.


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