Skip Navigation

European Heart Journal 1981 2(1):31-39;
Copyright © 1981 by the European Society of Cardiology.
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by SCHWARTZ, J.
Right arrow Articles by HARRISON, D. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by SCHWARTZ, J.
Right arrow Articles by HARRISON, D. C.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 1981, by The European Society Of Cardiology

A comparison of Circulatory responsiveness following the sudden withdrawal from atenolol and propranolol*

J. SCHWARTZ, G. JACKSON{dagger}, R. E. KATES and D. C. HARRISON

Cardiology Division Stanford University School of Medicine, Stanford, California U.S.A.

Received 16 June 1980; revised 28 October 1980; .

Requests for reprints to: Donald C. Harrison, M. D., Cardiology Division, Standford University School of Medicine, Palo Alto, Ca 94305 U.S.A.

Abstract

The sudden withdrawal of propranolol and atenolol was studied in five normal volunteers. Exercise testing was performed during the withdrawal period and physiological responsiveness compared to control responses. A significantly heightened reactivity of the blood pressure with early exercise was found after discontinuation of both drugs. A significant acceleration of the heart rale response with early exercise was seen only following propranolol withdrawal. When the combined effect (heart rate x systolic blood pressure) was analyzed, a significant increase in the double product achieved with low levels of exercise was observed following the sudden withdrawal of only propranolol administration.

Key Words: Circulatory responsiveness • atenolol • propranolol


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.