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European Heart Journal 1999 20(21):1538-1552; doi:10.1053/euhj.1999.1850
Copyright © 1999 by the European Society of Cardiology.
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Review

Evaluation of antiarrhythmic drug efficacy in patients with an ICD. Unlimited potential or replete with complexity and problems?

C.M Pratta,f1, A.J Cammb, J.T Bigger, Jrc, G Breithardtd, R.W.F Campbelle,f2, A.E Epsteinf, L.J Kappenbergerg, K.-H Kuckh, S Pococki, S Saksenaj and A.L Waldok

a Baylor College of Medicine, Houston, U.S.A.
b St. George's Hospital Medical School, London, U.K.
c Columbia University, New York, U.S.A.
d Westfälische-Wilhelms Universität, Münster, Germany
e Freeman Hospital, Newcastle upon Tyne, U.K.
f University of Alabama, Birmingham, U.S.A.
g CHUV, Lausanne, Switzerland
h St. Georg Krankenhauses, Hamburg, Germany
i London School of Hygiene & Tropical Medicine, London, U.K.
j Eastern Institute General Hospital, Passaic, U.S.A.
k Case Western Reserve University, Cleveland, U.S.A.

revised June 29, 1999; accepted July 7, 1999

Abstract

A report from a Study group, proposed by A. J. Camm, London, of the Working Groups on Arrhythmias and Cardiac Pacing of the European Society of Cardiology; co-sponsored by the North American Society of Pacing and Electrophysiology. The Study Group was convened on 29 August 1997 at Saltsjöbaden, near Stockholm. The meeting was chaired by A. J. Camm, London, and C. M. Pratt, Houston. Based on the presentation and discussions, a first draft of the documents was prepared by C. Pratt and J. Camm which was then circulated to all members three times for their review. All members of the Study Group approved the final manuscript. This report represents the opinion of the members of this Study Group and does not necessarily reflect the official position of either society.

The meeting of the Study Group was made possible by unrestricted educational grants from Medtronic, Guidant, Proctor & Gamble, Berlex and Sanofi.

Also, presented, in part, at the Cardio-Renal Drugs Advisory Board meeting of the Food and Drug Administration, Bethesda, Maryland, on 30 April 1999.

f1 Correspondence: Dr Craig Pratt, Professor of Medicine, Department of Internal Medicine, Section of Cardiology, Baylor College of Medicine, 6565 Fannin, M.S. F-1001, Houston, Texas 77030, U.S.A.

f2 This paper is dedicated to the memory of Ronald W. F. Campbell (Ronnie) whose enthusiasm for and insight into clinical cardiology research is truly missed.


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