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European Heart Journal 2000 21(1):28-32; doi:10.1053/euhj.1999.1634
Copyright © 2000 by the European Society of Cardiology.
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Determinants of mortality after cardiac surgery: results of the Registry of the Arbeitsgemeinschaft Leitender Kardiologischer Krankenhausärzte (ALKK) on 10525 Patients

A Vogta,f1, E Grubeb, H.G Glunzc, K.E Hauptmannd, U Sechteme, W Mäurerf, U Tebbeg, K.W Heinrichh, H.-J Engeli, W Kettnerj, W Krawietzk and K.-L Neuhausa

a Medizinische Klinik II, Städtische Kliniken gGmbH, Kassel
b Krankenhaus Siegburg GmbH, Medizinische Klinik, Siegburg
c Klinikum Westpfalz, Kaiserslautern
d Krankenhaus der Barmherzigen Brüder, Trier
e Robert-Bosch-Krankenhaus, Stuttgart
f Klinikum Bayreuth, Bayreuth
g Medizinische Klinik II, Klinikum Lippe-Detmold, Detmold
h Herzzentrum KWK, Duisburg
i Zentral-Krankenhaus Links der Weser, Bremen
j Klinik für Inner Medizin, Krankenhaus Altstadt, Magdeburg
k Medizinische Klinik I, Klinikum Rosenheim, Rosenheim, Germany

revised March 22, 1999; accepted March 26, 1999

Abstract

Background Mortality from cardiac surgery is an essential indicator of quality and forms the basis of treatment strategy decisions in eligible patients. No contemporary complete data on unselected adult cardiac surgery patients are available in Germany.

Methods and Results A registry was started in June 1997 of all patients referred to surgery from 85 cardiology centres in Germany. The registry was intended to include 10000 patients and this number was reached in March 1998. Follow-up of the patients was by simple questionnaire, reporting the date of surgery, major complications, and symptomatic improvement. If the questionnaire was not returned, a reminder letter was sent and, if necessary, further telephone investigations were performed. This resulted in 99·9% complete data. Of 10525 patients operated on, 3·91% had died by 30 days after surgery. The overall operative mortality was 4·57%, which included 69 patients who died after more than 30 days from complications related to surgery. By multivariate analysis, the following predictors of mortality were identified: previous surgery, emergency or complex operation; age >75 years, female gender, cardiac failure, angina CCS class IV, and three-vessel coronary disease. An integral part of the registry was a pre-operative prediction of surgical risk in five categories. This risk estimate revealed a surprisingly correct prediction of the mortality observed.

Conclusions In a representative unselected group of cardiac surgery patients, operative mortality was 4·57%. Several procedural and clinical parameters were significantly correlated with mortality, but the risk increment by each of these factors was small. Unstructured clinical judgement reliably predicted the operative risk.

Key Words: Cardiac surgery, bypass surgery, mortality, quality control.

f1 Correspondence: Prof. Dr. med. Albrecht Vogt, Medizinische Klinik II, Städtische Kliniken gGmbH, Mönchebergstraße 41–43, D-34125 Kassel, Germany.


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