Skip Navigation

European Heart Journal 2002 23(10):806-814; doi:10.1053/euhj.2001.2966
Copyright © 2002 by the European Society of Cardiology.
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (41)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Cohen-Solal, A.
Right arrow Articles by Dahan, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Cohen-Solal, A.
Right arrow Articles by Dahan, M.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

A non-invasively determined surrogate of cardiac power (‘circulatory power’) at peak exercise is a powerful prognostic factor in chronic heart failure

A. Cohen-Solalf1, J.Y. Tabet, D. Logeart, P. Bourgoin, M. Tokmakova and M. Dahan

Service de Cardiologie, Hôpital Beaujon, 92110, Clichy, France

revised August 7, 2001; accepted August 15, 2001

Abstract

Objectives This study was designed to assess the prognostic value of a new variable derived from a cardiopulmonary exercise test, the circulatory power, a surrogate of cardiac power, at peak exercise, in patients with chronic heart failure.

Background Peak exercise cardiac power and stroke work are invasive parameters with recently proven prognostic value. It is unclear whether these variables have better prognostic value than peak oxygen uptake (VO2).

Methods The study population comprised 175 patients with chronic heart failure (ejection fraction <45%) who underwent a cardiopulmonary exercise test. Circulatory power and circulatory stroke work were defined as the product of systolic arterial pressure and VO2 and oxygen pulse, respectively. Prognostic value was assessed by survival curves (Kaplan–Meier method) and uni- and multivariate Cox analyses.

Results With a mean follow-up of 25±10 months, ejection fraction, heart rate, systolic arterial pressure, peak VO2, VCO2, the anaerobic threshold, minute ventilation, the ventilatory equivalents of oxygen and carbon dioxide, the half times of VO2 and VCO2 recoveries, and the circulatory stroke work and power predicted outcome. Multivariate analysis demonstrated that the peak circulatory power (chi-square=19·9,P <0·001) (but not peak circulatory stroke work) was the only variable predictive of prognosis.

Conclusion The prognostic value of cardiopulmonary exercise tests in heart failure patients can be improved by assessing a new variable, the circulatory power—a surrogate of cardiac power—at peak exercise.

Key Words: Peak oxygen consumption, exercise, chronic heart failure, recovery, circulatory power, prognosis

f1 Correspondence: Pr Alain Cohen-Solal, Service de Cardiologie, Hôpital Beaujon, 100 Boulevard du General Leclerc, 92110 Clichy, France.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J Am Coll CardiolHome page
J. N. Kirkpatrick, M. A. Vannan, J. Narula, and R. M. Lang
Echocardiography in Heart Failure: Applications, Utility, and New Horizons
J. Am. Coll. Cardiol., July 31, 2007; 50(5): 381 - 396.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
M. Kindermann, B. Hennen, J. Jung, J. Geisel, M. Bohm, and G. Frohlig
Biventricular Versus Conventional Right Ventricular Stimulation for Patients With Standard Pacing Indication and Left Ventricular Dysfunction: The Homburg Biventricular Pacing Evaluation (HOBIPACE)
J. Am. Coll. Cardiol., May 16, 2006; 47(10): 1927 - 1937.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
P. Dall'Ago, G. R.S. Chiappa, H. Guths, R. Stein, and J. P. Ribeiro
Inspiratory Muscle Training in Patients With Heart Failure and Inspiratory Muscle Weakness: A Randomized Trial
J. Am. Coll. Cardiol., February 21, 2006; 47(4): 757 - 763.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
U. Corra, A. Mezzani, E. Bosimini, and P. Giannuzzi
Cardiopulmonary Exercise Testing and Prognosis in Chronic Heart Failure*: A Prognosticating Algorithm for the Individual Patient
Chest, September 1, 2004; 126(3): 942 - 950.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart J SupplHome page
F.X Kleber, P Waurick, and M Winterhalter
CPET in heart failure
Eur. Heart J. Suppl., August 1, 2004; 6(suppl_D): D1 - D4.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
R. V. Milani, C. J. Lavie, and M. R. Mehra
Cardiopulmonary Exercise Testing: How Do We Differentiate the Cause of Dyspnea?
Circulation, July 27, 2004; 110(4): e27 - e31.
[Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
R. Fincke, J. S. Hochman, A. M. Lowe, V. Menon, J. N. Slater, J. G. Webb, T. H. LeJemtel, G. Cotter, and SHOCK Investigators
Cardiac power is the strongest hemodynamic correlate of mortality in cardiogenic shock: A report from the SHOCK trial registry
J. Am. Coll. Cardiol., July 21, 2004; 44(2): 340 - 348.
[Abstract] [Full Text] [PDF]

Home page
 ChestHome page
G. Cotter, Y. Moshkovitz, E. Kaluski, A. J. Cohen, H. Miller, D. Goor, and Z. Vered
Accurate, Noninvasive Continuous Monitoring of Cardiac Output by Whole-Body Electrical Bioimpedance
Chest, April 1, 2004; 125(4): 1431 - 1440.
[Abstract] [Full Text] [PDF]

Home page
 CirculationHome page
P. Lancellotti, P. Troisfontaines, A.-C. Toussaint, and L. A. Pierard
Prognostic Importance of Exercise-Induced Changes in Mitral Regurgitation in Patients With Chronic Ischemic Left Ventricular Dysfunction
Circulation, October 7, 2003; 108(14): 1713 - 1717.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
D.P. Nicholls, C. O'Dochartaigh, and M.S. Riley
Circulatory power--a new perspective on an old friend
Eur. Heart J., August 2, 2002; 23(16): 1242 - 1245.
[PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.