Skip Navigation

European Heart Journal 2003 24(19):1788-1795; doi:10.1016/S0195-668X(03)00440-8
Copyright © 2003 by the European Society of Cardiology.
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow E-letters: Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when E-letters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (13)
Right arrowRequest Permissions
Right arrow Disclaimer
Google Scholar
Right arrow Articles by Diamantopoulos, L.
Right arrow Articles by Serruys, P. W
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Diamantopoulos, L.
Right arrow Articles by Serruys, P. W
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Preclinical research

The effect of reduced blood-flow on the coronary wall temperature

Are significant lesions suitable for intravascular thermography?

Leonidas Diamantopoulosa,*, Xiaoshun Liua, Ivan De Scheerder, Rob Kramsb, Shengiao Lia, Johan Van Cleemputa, Walter Desmeta and Patrick W Serruysb

a Cardiology Dept., University Gasthuisberg Leuven, Belgium
b Thoraxcenter, Erasmus University Rotterdam, Rotterdam, Netherlands

* Corresponding author. Leonidas Diamantopoulos MD, PhD, Department of Cardiology, University Hospital Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium. Tel.: +32-497459597; fax: +32-16604009
E-mail address: leo{at}otenet.gr

Received 20 February 2003; revised 2 July 2003; accepted 23 July 2003 This paper was guest edited by Prof. Antonio Colombo, EMO Centro Cuore Columbus S.r.l., Italy

Abstract

Aims The purpose of this study was to investigate the relation between acute coronary flow reduction and arterial wall temperature.

Methods and results Five pigs with normal coronary arteries were catheterized. Arterial wall temperature was studied with a thermographic system that uses a 4-thermistor sensor tip. Flow velocity was studied at the same time and place with the temperature measurements, using a Doppler wire. In order to modify the coronary flow, a balloon was gradually inflated proximally to the thermographic sensors. Temperature differences and flow velocities were simultaneously recorded.

Flow velocities above an average peak velocity (APV) of 9cm/s were associated with unaffected temperature measurements. At flow velocities around 4cm/s, the wall temperature was increased ({Delta}T=0.015±0.005oC, P~0.05), following the heart-rate. When flow velocity dropped further below this value, the local wall temperature was logarithmically increased to a maximum value observed at total vessel occlusion ({Delta}T=0.188±0.023oC, P<0.001).

Conclusion The reduction of coronary flow has an effect on the arterial wall temperature. This effect however, appears only below a critical threshold of APV and in a logarithmic fashion. Above this threshold, temperature measurements should be unaffected from flow reductions and related to the regional temperature heterogeneity.

Key Words: Thermography • Flow • Temperature • Inflammation • Vulnerable


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J Am Coll CardiolHome page
T. Takumi, S. Lee, S. Hamasaki, K. Toyonaga, D. Kanda, K. Kusumoto, H. Toda, T. Takenaka, M. Miyata, R. Anan, et al.
Limitation of Angiography to Identify the Culprit Plaque in Acute Myocardial Infarction With Coronary Total Occlusion: Utility of Coronary Plaque Temperature Measurement to Identify the Culprit Plaque
J. Am. Coll. Cardiol., December 4, 2007; 50(23): 2197 - 2203.
[Abstract] [Full Text] [PDF]

Home page
 Arterioscler. Thromb. Vasc. Bio.Home page
L. Rzeszutko, J. Legutko, G. L. Kaluza, M. Wizimirski, A. Richter, M. Chyrchel, G. Heba, J. S. Dubiel, and D. Dudek
Assessment of Culprit Plaque Temperature by Intracoronary Thermography Appears Inconclusive in Patients With Acute Coronary Syndromes
Arterioscler Thromb Vasc Biol, August 1, 2006; 26(8): 1889 - 1894.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
M. Madjid, J. T. Willerson, and S. W. Casscells
Intracoronary Thermography for Detection of High-Risk Vulnerable Plaques.
J. Am. Coll. Cardiol., April 18, 2006; 47(8S): C80 - C85.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
K. Toutouzas, E. Tsiamis, M. Vavuranakis, and C. Stefanadis
Coronary artery plaque temperature: what do we measure?
Eur. Heart J., June 1, 2004; 25(11): 993 - 994.
[Full Text] [PDF]


Disclaimer: Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.