Copyright © 2003 by the European Society of Cardiology.
Excellent survival and low incidence of arrhythmias, stroke and heart failure long-term after surgical ASD closure at young age
A prospective follow-up study of 21–33 years
a Departments of Cardiology and Cardiothoracic Surgery, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
b Department of Cardiothoracic Surgery, Thoraxcenter, Erasmus Medical Centre, Rotterdam,The Netherlands
c Department of Child and Adolescent Psychiatry, Sophia Children's Hospital, Rotterdam,The Netherlands
Received March 5, 2002; accepted May 23, 2002 * Correspondence: J. W. Roos-Hesselink, Thoraxcenter Ba 308, Erasmus Medical Centre Rotterdam, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
Aims Although studies have suggested good long-term results, arrhythmias, pulmonary hypertension and left ventricular dysfunction are mentioned as sequelae long-term after surgical atrial septal defect closure at young age. Most studies were performed only by questionnaire and in a retrospective manner. The long-term outcome is very important with regard to future employment and acceptance on insurance schemes.
Methods and Results One hundred and thirty-five consecutive ASD-patients, operated on in childhood, were studied longitudinally with ECG, echocardiography, exercise testing and Holter-recording 15 (10–22) and 26 (21–33) years after surgery. During follow-up no cardiovascular mortality, stroke, heart failure and no pulmonary hypertension occurred. Symptomatic supraventricular tachyarrhythmias were present in 6% after 15 years, and an additional 2% occurred in the last decade; 5% needed pacemaker implantation. No relation was found between arrhythmias and type of ASD, baseline data, right ventricular dimensions, or age at operation. Left and right ventricular function and dimension remained unchanged. Slightly more patients had right atrial dilatation at last follow-up. Exercise capacity was comparable with the normal Dutch population.
Conclusions The long-term outcome after ASD closure at young age shows excellent survival and low morbidity. The incidence of supraventricular arrhythmias is lower than in natural history studies of ASD patients and also lower than after surgical correction at adult age.
Key Words: Secundum atrial septal defect • heart surgery • long-term follow-up • supraventricular arrhythmias
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