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European Heart Journal 2004 25(12):1063-1069; doi:10.1016/j.ehj.2004.04.016
Copyright © 2004 by the European Society of Cardiology.
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Clinical research

Limited thoracotomy as a second choice alternative to transvenous implant for cardiac resynchronisation therapy delivery

Andrea Puglisia,*, Maurizio Lunatib, Antonino G.M Marulloc, Stefano Bianchia, Mariano Fecciad, Fabrizio Sgrecciaa, Ilaria Vicinie, Sergio Valsecchie, Francesco Musumecid and Ettore Vitalib

a Fatebenefratelli Hospital, Isola Tiberina, Rome, Italy
b Niguarda Ca'Granda Hospital, Milan, Italy
c "LaSapienza" University, Rome, Italy
d S. Camillo Hospital, Rome, Italy
e Medtronic Italy, Milan, Italy

* Corresponding author. Tel.: +39066837208; fax: +390668300746
E-mail address: puglisiandrea{at}hotmail.com

Received 24 November 2003; revised 18 March 2004; accepted 2 April 2004

Abstract

Aims Left ventricular (LV) pacing via transvenous implantation has an overall success rate ranging from 88% to 92%. The aim of this study was to assess whether LV pacing via limited thoracotomy would be feasible and safe when used on a routine basis for those cases in which standard transvenous procedures proved to be ineffective or unsatisfactory.

Methods and results We enrolled 33 patients (8 females, 65±10 years) who experienced a transvenous implantation failure. All patients underwent a limited thoracotomy and an epicardial lead was implanted. The procedure time was 51±28 min. No surgical or post-operative complications occurred and optimal lateral position was achieved for all patients. In the 12 months follow-up period, 5 patients died from refractory heart failure, the remaining patients did not experience complications. At implant, the mean pacing threshold was 1.3±0.7 V, bi-ventricular pacing impedance was 476±201 {Omega} and R-wave amplitude was 15.0±6.1 mV. No significant differences were found in any of the electrical parameters between baseline and follow-up. Significant improvement was observed in functional and echocardiographic parameters.

Conclusion Our results suggest that a combined approach to cardiac resynchronisation therapy delivery, including a transvenous attempt followed by a back up thoracotomic procedure, could potentially guarantee the success.

Key Words: Thoracotomy • Resynchronisation therapy • Heart failure


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