Copyright © 2004 by the European Society of Cardiology.
Clinical research
Visualisation and quantification of peri-operative myocardial infarction after coronary artery bypass surgery with contrast-enhanced magnetic resonance imaging
a Department of Cardiothoracic Surgery, University Hospital, SE-751 85 Uppsala, Sweden
b Department of Diagnostic Radiology, University Hospital, Uppsala, Sweden
c Department of Cardiology, University Hospital, Uppsala, Sweden
d Amersham Health, Oslo, Norway
* Corresponding author. Tel.: +46-18-6114040; fax: +46-18-551526
E-mail address: johnny.steuer{at}surgsci.uu.se
Received 17 December 2003; revised 11 May 2004; accepted 18 May 2004 See page 1279 for the editorial comment on this article.1
Abstract
Aims To evaluate if elevated biochemical marker levels after coronary artery bypass grafting (CABG) correspond to the amount of peri-operatively infarcted myocardium, quantified by magnetic resonance imaging (MRI) post-operatively.
Methods and results A total of 23 patients without evidence of previous myocardial infarction or myocarditis and with normal pre-operative ECG and left ventricular function and who underwent elective, primary CABG, without any other concomitant cardiac surgery, were included. Plasma creatinine kinase MB (CK-MB) and troponin I and T were measured on the first, second and fourth post-operative days. Between the fourth and ninth post-operative days, cardiac MRI was carried out. Infarctions were found in 18 patients. The infarction mass at MRI was numerically largest in patients with transmural infarctions, all of whom had a CK-MB more than five times the upper normal limit. All three cardiac markers correlated to the mass of infarction.
Conclusion Elevated biochemical markers after CABG correspond to the amount of peri-operatively infarcted myocardium.
Key Words: By-pass • Creatinine kinase • Magnetic resonance imaging
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