Copyright © 2004 by the European Society of Cardiology.
Clinical research
The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe
The Euro Heart Survey on diabetes and the heart
gorzata Bartnika,b,*
a Department of Cardiology, Karolinska University Hospital, Solna, Stockholm, Sweden
b 3rd Department of Cardiology, Silesian School of Medicine, Górno
laskie Centrum Medyczne, Katowice, Poland
c Chair of Cardiology, University of Ferrara and Fondazione S. Maugeri, Ferrara, Italy
d Department of Medicine, Kuopio University Hospital, Kuopio, Finland
e Thoraxcenter, Department of Cardiology, Erasmus University Medical Center, Rotterdam, The Netherlands
f Department of Medicine (Endocrinology), Teaching Hospital, Munich-Schwabing, Germany
g Service of Cardiology, Hospital Universitari Vall d'Hebron, Barcelona, Spain
h Department of Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden
Received April 6, 2004; revised July 8, 2004; accepted July 20, 2004 * Corresponding author. Tel.: +46 8 517 72171; fax: +46 8 31 10 44 (E-mail: malgorzata.bartnik{at}medks.ki.se).
See page 1865 for the editorial comment on this article (doi:10.1016/j.ehj.2004.07.027)
AIM: The objective behind the Euro Heart Survey on diabetes and the heart was to study the prevalence of abnormal glucose regulation in adult patients with coronary artery disease (CAD).
METHODS AND RESULTS: The survey engaged 110 centres in 25 countries recruiting 4196 patients referred to a cardiologist due to CAD out of whom 2107 were admitted on an acute basis and 2854 had an elective consultation. Patient data were collected via a web-based case record form. An oral glucose tolerance test (OGTT) was used for the characterisation of the glucose metabolism.
Thirty-one per cent of the patients had diabetes. An OGTT was performed on the 1920 patients without known diabetes, of whom 923 had acute and 997 had a stable manifestation of CAD, respectively. In patients with acute CAD, 36% had impaired glucose regulation and 22% newly detected diabetes. In the stable group these proportions were 37% and 14%.
CONCLUSION: This survey demonstrates that normal glucose regulation is less common than abnormal glucose regulation in patients with CAD. OGTT easily discloses the glucometabolic state and should be a routine procedure. The knowledge of glucometabolic state among these patients should influence their future management because it has great potential to improve the outcome.
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