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European Heart Journal 2004 25(9):723-727; doi:10.1016/j.ehj.2004.02.019
Copyright © 2004 by the European Society of Cardiology.
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Review

Fractional flow reserve and complex coronary pathologic conditions

William Kongto Hau*

Department of Physiology and Institute of Cardiovascular Science and Medicine, Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong

Received October 10, 2003; revised February 16, 2004; accepted February 19, 2004 * Tel.: +852-28199266/+852-93898229; fax: +852-28559730
E-mail address: kthau{at}attglobal.net

Fractional flow reserve (FFR) is a well-validated index for assessing the physiologic significance of a coronary stenosis in most clinical conditions encountered in today's catheterisation laboratory. The aim of this paper is to provide a short overview of the theoretical background of the coronary pressure-derived FFR index and its clinical applicability in guiding complex coronary intervention procedures.

Key Words: Fractional flow reserve • Pressure-sensing guidewire • Vasodilator • Hyperaemia


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