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European Heart Journal Advance Access originally published online on May 22, 2006
European Heart Journal 2006 27(14):1690-1698; doi:10.1093/eurheartj/ehl038
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© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Quality of life after coronary revascularization in the elderly

Michelle M. Graham1,*, Colleen M. Norris1,2, P. Diane Galbraith6, Merril L. Knudtson3,5, William A. Ghali3,4,6,{dagger} for the APPROACH Investigators

1 Division of Cardiology, Department of Medicine, University of Alberta Hospital, 8, 440-112 Street, Edmonton, Alberta, Canada T6G 2R7
2 Faculty of Nursing, University of Alberta, Alberta, Canada
3 the Department of Medicine, University of Calgary, Calgary, Canada
4 Community Health Sciences, University of Calgary, Calgary, Canada
5 The Libin Cardiovascular Institute, University of Calgary, Calgary, Canada
6 Centre for Health and Policy Studies, University of Calgary, Calgary, Canada

Received 14 July 2005; revised 31 March 2006; accepted 28 April 2006; online publish-ahead-of-print 22 May 2006.

* Corresponding author. Tel: +1 780 407 1590; fax: +1 780 407 1496. E-mail address: mmgraham{at}cha.ab.ca

See page 1642 for the editorial comment on this article (doi:10.1093/eurheartj/ehl111)

Aims To describe health status outcomes at 4 years for a cohort of elderly patients with cardiac disease.

Methods and results Using the Alberta Provincial Project for Outcomes Assessment in Coronary Heart Disease, an outcomes initiative capturing all patients undergoing cardiac catheterization in Alberta, Canada, health status was measured using the Seattle Angina Questionnaire (SAQ) and crude and risk-adjusted outcomes were determined and compared for patients treated with percutaneous coronary intervention or coronary artery bypass surgery (CABG) vs. medical therapy. Response rates among surviving, consenting patients were 64.8% for patients <70 years (n=7883), 77.3% for patients aged 70–79 years (n=2940), and 77.7% for patients ≥80 years of age (n=439). For patients aged <70 years, and those aged 70–79 years, for all dimensions of the SAQ, scores were significantly better for patients treated with revascularization procedures than with medical therapy. For patients over the age of 80 years, scores for patients treated with CABG in particular were significantly better, with the exception of exertional capacity. At 3 years, all scores remained stable or improved, and continued to favour revascularization.

Conclusion Elderly patients undergoing revascularization have better health status at 4 years than do those in the same age group who do not undergo revascularization. These findings suggest that age should not deter against revascularization given the combined survival and quality-of-life benefits.

Key Words: Aging • Revascularization • Coronary disease • Morbidity


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