Skip Navigation


European Heart Journal Advance Access originally published online on January 27, 2006
European Heart Journal 2006 27(9):1018-1025; doi:10.1093/eurheartj/ehi734
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
27/9/1018    most recent
ehi734v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (7)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Donal, E.
Right arrow Articles by Daubert, J.-C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Donal, E.
Right arrow Articles by Daubert, J.-C.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© The European Society of Cardiology 2006. All rights reserved. For Permissions, please e-mail: journals.permissions@oxfordjournals.org

Effects of cardiac resynchronization therapy on disease progression in chronic heart failure

Erwan Donal1, Christophe Leclercq1, Cecilia Linde2 and Jean-Claude Daubert1,*

1 Department of Cardiology, Hôpital Pontchaillou-CHU, 2, rue Henri Le Guilloux, 35033 Rennes, Cedex 09, France
2 Department of Cardiology, Karolinska University Hospital, Stockholm, Sweden

Received 2 July 2005; revised 17 December 2005; accepted 22 December 2005; online publish-ahead-of-print 27 January 2006.

* Corresponding author. Tel: +33 2 99 28 25 25; fax: +33 2 99 28 25 10. E-mail address: jean-claude.daubert{at}chu-rennes.fr

Despite the alleviation of symptoms and longer survival conferred by pharmacological management of chronic congestive heart failure (CHF), this progressive syndrome remains associated with high morbidity and premature death. A new treatment of CHF should ideally alleviate symptoms, improve functional capacity, decrease mortality, and slow or reverse its progression without adding risks for the patient that outweighs the benefits. Growing evidence indicates that devices implanted to resynchronize ventricular contraction are a beneficial adjunct in the treatment of CHF. This review discusses the remodelling process, and its clinical and prognostic significance. We also discuss the impact of CRT, on remodelling and disease progression with a particular focus on patients with asymptomatic or mild heart failure (NYHA Class I-II).

Key Words: Cardiac resynchronization therapy • Heart failure • Disease progression • Ventricular remodelling


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 J Am Coll CardiolHome page
C. Leclercq, F. Gadler, W. Kranig, S. Ellery, D. Gras, A. Lazarus, J. Clementy, E. Boulogne, J.-C. Daubert, and for the TRIP-HF (Triple Resynchronization In Paced
A Randomized Comparison of Triple-Site Versus Dual-Site Ventricular Stimulation in Patients With Congestive Heart Failure
J. Am. Coll. Cardiol., April 15, 2008; 51(15): 1455 - 1462.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart JHome page
I. Garcia-Bolao, B. Lopez, A. Macias, J. J. Gavira, P. Azcarate, and J. Diez
Impact of collagen type I turnover on the long-term response to cardiac resynchronization therapy
Eur. Heart J., April 1, 2008; 29(7): 898 - 906.
[Abstract] [Full Text] [PDF]

Home page
 EuropaceHome page
M. W. Kimmel, N. D. Skadsberg, C. L. Byrd, D. J. Wright, T. G. Laske, and P. A. Iaizzo
Single-site ventricular and biventricular pacing: investigation of latest depolarization strategy
Europace, December 1, 2007; 9(12): 1163 - 1170.
[Abstract] [Full Text] [PDF]

Home page
 Eur Heart J SupplHome page
S. H. Hohnloser and E. N. Prystowsky
CRT-D use in heart failure: too little or too much?
Eur. Heart J. Suppl., September 1, 2007; 9(suppl_G): G9 - G16.
[Abstract] [Full Text] [PDF]

Home page
 EuropaceHome page
C. Schmidt, J. Frielingsdorf, M. Debrunner, R. Tavakoli, M. Genoni, E. Straumann, O. Bertel, and B. Naegeli
Acute biventricular pacing after cardiac surgery has no influence on regional and global left ventricular systolic function
Europace, June 1, 2007; 9(6): 432 - 436.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.