Skip Navigation


European Heart Journal Advance Access originally published online on September 27, 2007
European Heart Journal 2007 28(22):2714-2719; doi:10.1093/eurheartj/ehm403
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
28/22/2714    most recent
ehm403v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (3)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Palmerini, T.
Right arrow Articles by De Servi, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Palmerini, T.
Right arrow Articles by De Servi, S.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2007. For permissions please email: journals.permissions@oxfordjournals.org

A comparison between coronary artery bypass grafting surgery and drug eluting stent for the treatment of unprotected left main coronary artery disease in elderly patients (aged ≥75 years)

Tullio Palmerini1,*, Fabio Barlocco2, Andrea Santarelli3, Letizia Bacchi-Reggiani1, Carlo Savini4, Elisa Baldini2, Laura Alessi1, Michele Ruffini3, Germano Di Credico5, Giancarlo Piovaccari3, Roberto Di Bartolomeo4, Antonio Marzocchi1, Angelo Branzi1 and Stefano De Servi2

1 Istituto di Cardiologia, Università di Bologna, Policlinico S. Orsola, Via Massarenti 9, 40 138 Bologna, Italy
2 Dipartimento di Cardiologia, Legnano, Italy
3 Dipartimento di Cardiologia, Rimini, Italy
4 Istituto di Cardiochirurgia, Policlinico S. Orsola, Bologna, Italy
5 Dipartimento Cardiochirurgia, Legnano

Received 5 June 2007; revised 14 August 2007; accepted 23 August 2007; online publish-ahead-of-print 27 September 2007.

* Corresponding author. Tel: +39 051 349858; fax: +39 051 344859. E-mail address: tulliopalmerini{at}hotmail.com

Aims: In this study, we compared the clinical outcomes of elderly patients with unprotected left main coronary artery (ULMCA) stenosis treated with either coronary artery bypass grafting (CABG) or drug-eluting stent (DES).

Methods and results: From January 2003 to April 2006, 259 patients with ULMCA stenosis and age ≥75 years underwent coronary revascularization with either CABG or DES. One hundred and sixty-one patients were treated with CABG and 98 with DES. The cumulative unadjusted rates of 2-year mortality were 17% in CABG-treated patients and 18% in those treated with DES (P = 0.71). The adjusted rates of 2-year survival were 85% for CABG-treated patients and 87% for DES-treated patients (P = 0.74). The incidence of 2-year myocardial infarction was 6% in CABG-treated patients and 4% in DES-treated patients (P = 0.11). The incidence of target lesion revascularization (TLR) was 3% in CABG-treated patients and 25% in DES-treated patients (P < 0.0001). In the multivariable analysis, peripheral vascular disease, left ventricular ejection fraction and acute coronary syndrome were independent predictors of 2-year mortality.

Conclusion: In this study, we could not demonstrate a difference in mortality between CABG-treated patients and those treated with DES. However, the rate of TLR was higher in the DES group.

Key Words: Stents • Bypass • Coronary disease


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Eur. J. Cardiothorac. Surg.Home page
A. J. Rastan, E. Boudriot, V. Falk, A. P. Kappetein, M. A. Borger, P. W. Serruys, G. Schuler, and F. W. Mohr
Frequency and pattern of de-novo three-vessel and left main coronary artery disease; insights from single center enrolment in the SYNTAX study
Eur. J. Cardiothorac. Surg., August 1, 2008; 34(2): 376 - 383.
[Abstract] [Full Text] [PDF]

Home page
 J Am Coll CardiolHome page
J. Brinker
The left main facts: faced, spun, but alas too few.
J. Am. Coll. Cardiol., March 4, 2008; 51(9): 893 - 898.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.